GSI-953
GSI-953 (CAS 769169-27-9), with the molecular formula C9H8ClF6NO3S2 and a molecular weight of 391.74, is a white to tan powder. This compound is recognised for its role in approved therapeutics and drug candidates, as well as its utility in bioactive small molecule research. It finds applications in cell biology and cell signalling studies, particularly within neuroscience research, and is a noted Pfizer compound.
- IUPAC
- Begacestat; 5-Chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxymethyl)-2- (trifluoromethyl)propyl] thiophene-2-sulfonamide
- Synonyms
- Begacestat5-Chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxymethyl)-2-(trifluoromethyl)propyl] thiophene-2-sulfonamide

Approved Therapeutics and Drug Candidates
GSI-953 is identified as a compound relevant to the development of approved therapeutics and drug candidates, suggesting its potential in pharmaceutical research and development.
Bioactive Small Molecule Research
This molecule functions as a bioactive small molecule, making it valuable for researchers investigating cellular processes and molecular interactions.
Cell Biology and Signalling
GSI-953 is utilised in cell biology studies, particularly within the realm of cell signalling, contributing to a deeper understanding of cellular mechanisms.
Neuroscience Research
The compound is applied in neuroscience research, aiding investigations into the complex systems and functions of the nervous system.
| Molecular weight | 391.74 |
|---|---|
| Empirical formula | C9H8ClF6NO3S2 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to tan |
| Solubility | DMSO: ≥15 mg/mL |
| Storage temperature | 2-8°C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is GSI-953 used for?
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GSI-953 is used in areas such as approved therapeutics and drug candidates, bioactive small molecule research, cell biology, cell signalling, and neuroscience research. It is also identified as a Pfizer compound.
What are the CAS number and formula for GSI-953?
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The CAS number for GSI-953 is 769169-27-9, and its empirical formula is C9H8ClF6NO3S2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies GSI-953 with a purity of ≥98% as determined by HPLC. We do not represent this product as USP, BP, or EP grade.
How should GSI-953 be handled and stored?
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GSI-953 is classified under WGK Germany 3. It should be stored at 2-8°C. Appropriate laboratory safety precautions should be observed during handling.
How is GSI-953 shipped and exported?
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GSI-953 is available for purchase and export globally. Shipping and handling adhere to international regulations for chemical substances. Please contact us for specific export details.
How can I request a sample or quote for GSI-953?
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To request a sample or a quote for GSI-953, please contact our sales department via the website or by phone. Our team will respond promptly to your inquiry.
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