Glycidol
Glycidol (CAS 556-52-5, C3H6O2) is a reactive organic compound, a colorless liquid with a molar mass of 74.08 g/mol. It serves as a key intermediate and building block in organic synthesis, particularly in the production of pharmaceuticals, polymers, and specialty chemicals. Its epoxide ring allows for diverse chemical transformations, making it valuable in various research and industrial applications.
- IUPAC
- (±)-Glycidol,(±)-Oxirane-2-methanol,2,3-Epoxy-1-propanol,Glycerolglycide
- Synonyms
- (±)-Glycidol(±)-Oxirane-2-methanol2,3-Epoxy-1-propanolGlycerolglycide
Pharmaceutical Synthesis
Glycidol is used as a crucial intermediate in the synthesis of various active pharmaceutical ingredients (APIs) and complex drug molecules. Its epoxide functionality enables the introduction of hydroxyl and other functional groups required for specific therapeutic agents.
Polymer Chemistry
This epoxide can be polymerised or incorporated into polymer structures. It finds use in the modification of polymers to impart specific properties, such as improved adhesion or solubility, in materials science applications.
Specialty Chemical Production
Glycidol acts as a versatile building block for the creation of diverse specialty chemicals. It is employed in the synthesis of surfactants, resins, and cross-linking agents for various industrial uses.
Organic Synthesis Intermediate
As a highly reactive epoxide, Glycidol is a valuable reagent in general organic synthesis. It readily undergoes ring-opening reactions with nucleophiles, facilitating the formation of carbon-carbon and carbon-heteroatom bonds.
| Molecular weight | 74.08 |
|---|---|
| Empirical formula | C3H6O2 |
| Assay | 96% |
| Boiling point | 61-62 °C/15 mmHg(lit.) |
| Density | 1.117 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.433(lit.) |
| Vapour pressure | 0.9 mmHg (25 °C) |
| Vapour density | 2.15 (vs air) |
| Autoignition temp | 780 °F |
| Storage temperature | 2-8°C |
| Impurities tested | ≤2% diglycidyl ether |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H331Toxic if inhaled
- H335May cause respiratory irritation
- H341Suspected of causing genetic defects
- H350May cause cancer
- H360F
Precautionary statements
- P201Obtain special instructions before use
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 81 °C / 177.8 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 45-60-21/22-23-36/37/38-68 |
| Safety statements (S) | 53-26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Glycidol used for?
+
Glycidol is used as a versatile building block and intermediate in pharmaceutical synthesis, polymer chemistry, and the production of various specialty chemicals. It is also a key reagent in general organic synthesis due to its reactive epoxide ring.
What is the CAS number and chemical formula for Glycidol?
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The CAS number for Glycidol is 556-52-5, and its chemical formula is C3H6O2.
What grade and purity does Tech Serve Solutions supply for Glycidol?
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Tech Serve Solutions supplies Glycidol with an assay of 96%. We do not represent this product as USP, BP, or EP grade.
How should Glycidol be handled safely?
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Glycidol is a dangerous substance. Handle with extreme care, wearing appropriate personal protective equipment including eyeshields, face shields, gloves, and a full-face or appropriate respirator, in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive guidance.
Is Glycidol a controlled substance?
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The provided data does not indicate that Glycidol is a controlled substance.
How is Glycidol packed, shipped, and exported?
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Glycidol is shipped under UN 2810, 6.1/PGIII regulations. Specific packaging details are available upon request, and TSS exports globally.
How can I request a sample or quote for Glycidol?
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To request a sample or a quote for Glycidol, please contact our sales department through the website or by phone.
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