Ganaxolone
Ganaxolone (CAS: 38398-32-2), a synthetic neurosteroid with the formula C22H36O2, is a selective positive allosteric modulator of GABAA receptors. It functions as an antagonist at NMDA receptors and exhibits other central nervous system effects. This white, solid compound is primarily utilised in neuroscience research for its role in modulating neurotransmission and exploring cellular signaling pathways.
- IUPAC
- 3α-Hydroxy-3β-methyl-5α-pregnan-20-one,CCD 1042
Neuroscience Research
Ganaxolone serves as a valuable tool in neuroscience to investigate the complex mechanisms of neurotransmission and GABAA receptor modulation. Its selective action aids in understanding neuronal excitability and the role of neurosteroids in brain function.
Cell Signaling Studies
This compound is employed in research focused on cell signaling pathways within the central nervous system. It helps researchers elucidate how neurosteroids interact with ion channels and receptor systems.
Bioactive Small Molecule Research
As a bioactive small molecule, Ganaxolone is used to study its effects on biological systems, particularly in areas related to GABAA receptor activity and excitatory amino acid pathways.
| Molecular weight | 332.52 |
|---|---|
| Empirical formula | C22H36O2 |
| Assay | (The product is pure based on elemental analysis, NMR, MS, optical rotation and melting point.)≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: ≥2 mg/mLH2O: insoluble |
| Storage temperature | 2-8°C |
| Gene Information | human ... GABRA1(2554)mouse ... Gabrg2(14406) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ganaxolone used for?
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Ganaxolone is used in neuroscience research to study GABAA receptor modulation, neuronal excitability, cell signaling, and neurotransmission. It acts as a selective positive allosteric modulator of GABAA receptors and an antagonist at NMDA receptors.
What is the CAS number and formula for Ganaxolone?
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The CAS number for Ganaxolone is 38398-32-2, and its empirical formula is C22H36O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ganaxolone with a purity of ≥98% (HPLC). This product is intended for research purposes and is not supplied as USP, BP, or EP grade.
How should Ganaxolone be stored and handled?
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Ganaxolone should be stored at 2-8°C. Based on the WGK Germany rating of 3, it is considered hazardous to water and requires careful handling to prevent environmental release.
How is Ganaxolone packed, shipped, and exported?
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Ganaxolone is supplied as a white solid and can be shipped and exported globally by Tech Serve Solutions according to regulatory standards for chemical compounds.
How can I request a sample or quote for Ganaxolone?
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To request a sample or a quote for Ganaxolone, please contact the Tech Serve Solutions sales team through our website or by phone.
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