Ethylenediamine dihydrochloride
Ethylenediamine dihydrochloride (CAS 333-18-6) is a chemical compound with the formula NH2CH2CH2NH2 · 2HCl and a molecular weight of 133.02 g/mol. This amine salt serves as a valuable building block in organic synthesis. Its applications include analytical chemistry for the determination of catecholamines and in the study of luminescence properties of lanthanide complexes, as well as in the synthesis of specific organic molecules.
- IUPAC
- 1,2-Diaminoethane dihydrochloride
- Synonyms
- 1,2-Diaminoethane dihydrochloride

Analytical Chemistry Reagent
Ethylenediamine dihydrochloride is utilized in modified ethylenediamine condensation methods for the fluorimetric determination of catecholamines, providing a sensitive analytical approach.
Coordination Chemistry Research
It is employed to investigate the luminescence properties of complexes formed between lanthanide ions such as Eu(III) and Tb(III) and ethylenediamine, aiding in materials science research.
Organic Synthesis Intermediate
The compound serves as a precursor in the synthesis of various organic molecules, including heterocyclic compounds like 1,3,5-tris(4,5-dihydro-1H-imidazol-2-yl)benzene.
| Molecular weight | 133.02 |
|---|---|
| Linear formula | NH2CH2CH2NH2 · 2HCl |
| Assay | 98% |
| Solubility | water: soluble100 mg/mL, clear, colorless to very faintly yellow |
| Application | Ethylenediamine dihydrochloride was used in modified ethylenediamine condensation method for fluorimetric determination of catecholamines1. It was used to investigate the luminescence properties of complexes of EuIII and TbIII with ethylenediamine2. It was used in the synthesis of 1,3,5-tris(4,5-dihydro-1H-imidazol-2-yl)benzene3. |
| Melting point | >300 °C(lit.) |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38-42/43 |
| Safety statements (S) | 22-26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethylenediamine dihydrochloride used for?
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Ethylenediamine dihydrochloride is used in analytical chemistry for the determination of catecholamines, in coordination chemistry research to study lanthanide complexes, and as a building block in organic synthesis for creating compounds like 1,3,5-tris(4,5-dihydro-1H-imidazol-2-yl)benzene.
What are the CAS number and formula for Ethylenediamine dihydrochloride?
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The CAS number for Ethylenediamine dihydrochloride is 333-18-6, and its linear formula is NH2CH2CH2NH2 · 2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethylenediamine dihydrochloride with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Ethylenediamine dihydrochloride be handled safely?
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Ethylenediamine dihydrochloride is harmful if swallowed, causes skin irritation, may cause an allergic skin reaction, causes serious eye irritation, and may cause allergy or asthma symptoms or breathing difficulties if inhaled. It can also cause respiratory irritation. Always use appropriate personal protective equipment, including a dust mask (N95), eyeshields, face shield, and gloves, and ensure adequate ventilation. Handle with extreme care and avoid inhalation, ingestion, and contact with skin and eyes.
Is Ethylenediamine dihydrochloride a controlled substance?
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The provided data does not indicate that Ethylenediamine dihydrochloride is a controlled substance.
How is Ethylenediamine dihydrochloride packed and exported?
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Ethylenediamine dihydrochloride is carefully packed according to industry standards to ensure safe transit and is available for export worldwide by Tech Serve Solutions.
How can I request a quote or sample of Ethylenediamine dihydrochloride?
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To request a quote or a sample of Ethylenediamine dihydrochloride, please contact the Tech Serve Solutions sales team through our website or by phone.
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