Ethyl thioglycolate
Ethyl thioglycolate (CAS: 623-51-8), with the linear formula HSCH₂COOC₂H₅ and a molecular weight of 120.17 g/mol, is a versatile organic compound. This clear liquid serves as a valuable intermediate in chemical synthesis, particularly in the production of pharmaceuticals and agrochemicals. Its distinct sulfur and ester functionalities allow for diverse chemical transformations.
- IUPAC
- Ethyl mercaptoacetate
- Synonyms
- Ethyl mercaptoacetate

Pharmaceutical Intermediate
Ethyl thioglycolate is employed in the synthesis of various active pharmaceutical ingredients (APIs). Its reactivity facilitates the introduction of sulfur-containing moieties crucial for certain drug structures.
Agrochemical Synthesis
This compound acts as a building block for the development of pesticides and herbicides. It contributes to the creation of molecules with specific biological activities for crop protection.
Organic Synthesis Reagent
Utilised in general organic chemistry, ethyl thioglycolate can participate in reactions such as alkylations and esterifications. It is a useful reagent for introducing the thioglycolate functional group.
| Molecular weight | 120.17 |
|---|---|
| Linear formula | HSCH2COOC2H5 |
| Assay | 97% |
| Boiling point | 54 °C/12 mmHg(lit.) |
| Density | 1.096 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.457(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 47 °C / 116.6 °F |
| Transport (UN / ADR) | UN 1992 3/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 10-25-36/38 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl thioglycolate used for?
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Ethyl thioglycolate is primarily used as an intermediate in pharmaceutical and agrochemical synthesis, and as a general reagent in organic chemistry.
What are the CAS number and formula for Ethyl thioglycolate?
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The CAS number for Ethyl thioglycolate is 623-51-8, and its linear formula is HSCH₂COOC₂H₅.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl thioglycolate with a minimum assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should Ethyl thioglycolate be handled safely?
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Ethyl thioglycolate is a flammable liquid and is toxic if swallowed and causes skin and serious eye irritation. Handle with appropriate personal protective equipment, including gloves, eyeshields, and a suitable respirator, in a well-ventilated area. Refer to the Safety Data Sheet for detailed handling instructions.
Is Ethyl thioglycolate a controlled substance?
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Based on the provided data, Ethyl thioglycolate is not listed as a controlled substance. However, users should always verify local regulations.
How is Ethyl thioglycolate packed, shipped, and exported?
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Ethyl thioglycolate is securely packaged according to international shipping regulations for hazardous materials. Tech Serve Solutions has extensive experience in exporting chemicals globally.
How can I request a sample or quote for Ethyl thioglycolate?
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To request a sample or a quotation for Ethyl thioglycolate, please contact our sales department through the website or via direct inquiry.
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