Ethyl 4-thiazolecarboxylate
Ethyl 4-thiazolecarboxylate (CAS: 14527-43-6; Formula: C6H7NO2S; MW: 157.19) is a key heterocyclic building block. This compound serves as a valuable intermediate in organic synthesis, particularly within the pharmaceutical and fine chemical industries. Its structure, featuring a thiazole ring functionalised with an ethyl ester group, allows for diverse chemical transformations, making it a sought-after reagent for constructing more complex molecules.
- IUPAC
- Thiazole-4-carboxylic acid ethyl ester
Pharmaceutical Intermediate
Ethyl 4-thiazolecarboxylate is utilised in the synthesis of various active pharmaceutical ingredients (APIs). Its heterocyclic nature is common in many drug scaffolds, enabling the development of novel therapeutic agents.
Chemical Synthesis
As a versatile building block, it is employed in general organic synthesis for creating novel compounds. The ester functionality can be readily modified or used in coupling reactions.
Research and Development
This compound is an important reagent for researchers exploring new chemical pathways and designing novel molecular architectures. It is frequently used in academic and industrial R&D laboratories.
| Molecular weight | 157.19 |
|---|---|
| Empirical formula | C6H7NO2S |
| Assay | 97% |
| Melting point | 51-55 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Flash point | >110 °C / >230 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl 4-thiazolecarboxylate used for?
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Ethyl 4-thiazolecarboxylate is primarily used as a building block in organic synthesis, including the development of pharmaceutical intermediates and other fine chemicals.
What are the CAS number and formula for Ethyl 4-thiazolecarboxylate?
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The CAS number is 14527-43-6, and the empirical formula (Hill notation) is C6H7NO2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl 4-thiazolecarboxylate with a minimum assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Ethyl 4-thiazolecarboxylate be handled?
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Caution is advised when handling. This compound is a warning irritant to skin, eyes, and respiratory tract (H315-H319-H335). Wear appropriate personal protective equipment, avoid breathing dust/fume/gas/mist/vapours/spray, and ensure adequate ventilation. In case of contact with eyes, rinse cautiously with water for several minutes (P305 + P351 + P338).
Is Ethyl 4-thiazolecarboxylate a controlled substance?
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Based on the provided data, Ethyl 4-thiazolecarboxylate is not indicated as a controlled substance.
How is Ethyl 4-thiazolecarboxylate packed and shipped?
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Tech Serve Solutions exports fine chemicals globally, adhering to all necessary shipping and handling regulations for safe international transit.
How can I request a sample or quote for Ethyl 4-thiazolecarboxylate?
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To request a sample or a quotation, please contact our sales team via the website or provide your requirements through the product enquiry form.
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