Ethyl 2-bromopropionate
Ethyl 2-bromopropionate (CAS 535-11-5) is a chiral organic compound with the linear formula CH3CHBrCOOC2H5 and a molecular weight of 181.03 g/mol. This flammable liquid, characterised by its refractive index of n20/D 1.446, serves as a valuable building block in organic synthesis. It is frequently employed in the preparation of more complex molecules within the pharmaceutical and fine chemical industries.
Organic Synthesis Intermediate
Ethyl 2-bromopropionate acts as a key intermediate in the synthesis of various organic compounds. Its reactive bromine atom allows for facile nucleophilic substitution reactions, enabling the introduction of the propionate ester moiety into target molecules.
Pharmaceutical Precursor
This compound is utilized in the multi-step synthesis of active pharmaceutical ingredients (APIs) and drug intermediates. Its structure lends itself to building chiral centres or incorporating specific functional groups required for therapeutic activity.
Chiral Building Block
As a chiral ester, it can be employed in asymmetric synthesis to create enantiomerically enriched products. This is crucial for developing stereospecific drugs and fine chemicals where precise stereochemistry is essential.
| Molecular weight | 181.03 |
|---|---|
| Linear formula | CH3CHBrCOOC2H5 |
| Assay | 99% |
| Boiling point | 156-160 °C(lit.) |
| Density | 1.394 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.446(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 51 °C / 123.8 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-34 |
| Safety statements (S) | 16-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl 2-bromopropionate primarily used for?
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Ethyl 2-bromopropionate is primarily used as a versatile building block and intermediate in organic synthesis, particularly in the pharmaceutical and fine chemical industries for creating more complex molecules and active pharmaceutical ingredients.
What is the CAS number and chemical formula for Ethyl 2-bromopropionate?
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The CAS number for Ethyl 2-bromopropionate is 535-11-5, and its linear chemical formula is CH3CHBrCOOC2H5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl 2-bromopropionate with a minimum purity of 99% as indicated by its assay. This is a technical grade suitable for research and synthesis; TSS does not represent it as USP, BP, or EP.
How should Ethyl 2-bromopropionate be handled safely?
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Ethyl 2-bromopropionate is a flammable liquid and causes severe skin burns and eye damage. Handle with extreme caution in a well-ventilated area, wearing appropriate personal protective equipment including gloves, goggles, face shield, and a suitable respirator. Store away from heat and ignition sources.
Is Ethyl 2-bromopropionate a controlled substance?
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Based on the provided data, Ethyl 2-bromopropionate is not listed as a controlled substance. However, users should always verify local regulations regarding its handling and use.
How is Ethyl 2-bromopropionate packed, shipped, and exported?
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Ethyl 2-bromopropionate is packed in accordance with safety regulations for hazardous materials. As a global supplier, Tech Serve Solutions exports this chemical internationally, adhering to all relevant shipping and customs requirements for dangerous goods (UN 2920, Class 3/8).
How can I request a sample or quote for Ethyl 2-bromopropionate?
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To request a sample or a quotation for Ethyl 2-bromopropionate, please contact the Tech Serve Solutions sales team via our website or direct inquiry channels, providing your specific requirements.
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