(−)-Epothilone B
(−)-Epothilone B (CAS: 152044-54-7; Formula: C27H41NO6S; MW: 507.68) is a potent antimitotic agent, isolated from the myxobacterium Sorangium cellulosum. It functions by promoting microtubule assembly and stabilization, thereby inhibiting cell division. This molecule is a valuable tool in research for studying apoptosis and cell cycle regulation, and it serves as a lead compound in the development of novel anti-cancer therapeutics.
- IUPAC
- EPO906,EpoB,Patupilone
Cancer Research
Investigates novel anti-cancer therapeutics by targeting microtubule dynamics and inducing apoptosis in rapidly dividing cancer cells. Serves as a lead compound for drug discovery programs.
Cell Biology Studies
Used to probe mechanisms of cell division, microtubule function, and the cell cycle. Its specific action on microtubules makes it a key reagent for cell cycle research.
Apoptosis Research
Investigates the pathways of programmed cell death, as Epothilone B can trigger apoptotic cascades in various cell types.
Chemical Synthesis Intermediate
Acts as a starting material or intermediate in the synthesis of complex natural products and related analogues for further biological evaluation.
| Molecular weight | 507.68 |
|---|---|
| Empirical formula | C27H41NO6S |
| Assay | ≥98% (HPLC) |
| Form | film |
| Colour | colorless |
| Storage temperature | −20°C |
| Biological source | from Sorangium cellulosum |
| Storage Condition | desiccatedprotect from light |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (–)-Epothilone B used for?
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(–)-Epothilone B is used in research for studying apoptosis and cell cycle regulation, and as a lead compound in the development of anti-cancer therapeutics.
What is the CAS number and chemical formula for (–)-Epothilone B?
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The CAS number is 152044-54-7, and the chemical formula is C27H41NO6S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (–)-Epothilone B with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
What are the safety and handling recommendations for (–)-Epothilone B?
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According to GHS, this substance is harmful if swallowed and causes skin irritation. It requires careful handling to avoid ingestion and skin contact. Storage at -20°C, desiccated and protected from light, is recommended.
How is (–)-Epothilone B typically shipped or exported?
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As a specialist global supplier, Tech Serve Solutions exports (–)-Epothilone B under appropriate conditions to ensure product integrity during transit.
How can I request a sample or quote for (–)-Epothilone B?
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Please contact our sales department via the website to request a sample or obtain a quotation for (–)-Epothilone B.
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