Domiphen bromide
Domiphen bromide (CAS: 538-71-6) is a quaternary ammonium compound with the molecular formula CH3(CH2)11N(CH3)2(CH2CH2OC6H5)Br and a molecular weight of 414.46 g/mol. It functions as a cationic surfactant and antiseptic agent. Domiphen bromide is primarily utilised in chemical synthesis and as a phase transfer catalyst due to its amphipathic nature, facilitating reactions between different phases.
- IUPAC
- (Dodecyldimethyl-2-phenoxyethyl)ammonium bromide
- Synonyms
- (Dodecyldimethyl-2-phenoxyethyl)ammonium bromide

Chemical Synthesis
As a quaternary ammonium salt, Domiphen bromide can be employed as a phase transfer catalyst. Its amphiphilic structure allows it to bridge the interface between aqueous and organic phases, promoting reactions that involve reactants from both phases.
Antiseptic Agent
Domiphen bromide exhibits antimicrobial properties and has historically been used in antiseptic preparations. Its cationic nature allows it to interact with and disrupt the cell membranes of microorganisms.
Surfactant
Possessing a long alkyl chain and a charged head group, Domiphen bromide acts as a cationic surfactant. This property makes it useful in applications requiring surface tension reduction or emulsification.
| Molecular weight | 414.46 |
|---|---|
| Linear formula | CH3(CH2)11N(CH3)2(CH2CH2OC6H5)Br |
| Assay | 97% |
| Melting point | 117-119 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Domiphen bromide used for?
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Domiphen bromide is primarily used in chemical synthesis as a phase transfer catalyst and also possesses antiseptic and surfactant properties.
What is the CAS number and molecular formula for Domiphen bromide?
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The CAS number for Domiphen bromide is 538-71-6, and its molecular formula is CH3(CH2)11N(CH3)2(CH2CH2OC6H5)Br.
What grade and purity does Tech Serve Solutions supply for Domiphen bromide?
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Tech Serve Solutions supplies Domiphen bromide with an assay of 97%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
What are the key safety considerations when handling Domiphen bromide?
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Domiphen bromide is classified with GHS07 and the signal word Warning. It can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment including eyeshields, gloves, and a dust mask (N95) should be used.
How is Domiphen bromide packed, shipped, and exported?
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Domiphen bromide is packed and shipped according to international regulations for hazardous materials. As a specialist global supplier, Tech Serve Solutions handles the export of chemicals, ensuring compliance with all relevant shipping and customs requirements.
How can I request a quote or sample of Domiphen bromide?
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To request a quote or a sample of Domiphen bromide, please contact our sales team via the website or by telephone, providing your contact details and the quantity required.
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