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DL-tert-Leucine

CAS 33105-81-6(CH3)3CCH(NH2)COOHChemical Synthesis

DL-tert-Leucine (CAS: 33105-81-6) is a non-proteinogenic amino acid with the linear formula (CH3)3CCH(NH2)COOH and a molecular weight of 131.17 g/mol. This chiral compound is primarily utilised in chemical biology and synthesis, particularly in the development of peptide chemistry and unnatural amino acid derivatives. Tech Serve Solutions supplies DL-tert-Leucine with a high purity of 98%, supporting research and development activities.

IUPAC
(±)-2-Amino-3,3-dimethylbutyric acid,DL-α-tert-Butylglycine
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DL-tert-Leucine ((CH3)3CCH(NH2)COOH) — chemical structure, CAS 33105-81-6; Chemistry, fine chemical supplied by Tech Serve Solutions
Chemical BiologyChemical SynthesisLeucine DerivativesPeptide Chemistry
01 /Applications

Peptide Synthesis

DL-tert-Leucine serves as a valuable building block in the synthesis of peptides, particularly for creating sterically hindered or unnatural peptide sequences. Its bulky tert-butyl side chain can influence peptide conformation and stability.

Chemical Biology Research

As an unnatural amino acid derivative, it is employed in chemical biology to probe protein structure-function relationships or to create novel biomolecules. It allows researchers to introduce non-natural structural motifs into biological systems.

Organic Synthesis Intermediate

The compound acts as an intermediate in various organic synthesis pathways. Its unique structure makes it useful for constructing complex organic molecules and chiral compounds.

Drug Discovery and Development

DL-tert-Leucine can be incorporated into potential drug candidates to modify their pharmacokinetic properties, such as metabolic stability or receptor binding affinity. Its inclusion may lead to novel therapeutic agents.

02 /Properties
Molecular weight131.17
Linear formula(CH3)3CCH(NH2)COOH
Assay98%
Melting point>300 °C(lit.)
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
33105-81-6
MDL number
MFCD00065933
PubChem substance
24874861
Beilstein registry
1721823
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is DL-tert-Leucine used for?

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DL-tert-Leucine is primarily used in chemical biology and synthesis, particularly in peptide chemistry and as an unnatural amino acid derivative. It also serves as an intermediate in organic synthesis and finds applications in drug discovery.

What is the CAS number and formula for DL-tert-Leucine?

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The CAS number for DL-tert-Leucine is 33105-81-6. Its linear formula is (CH3)3CCH(NH2)COOH.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies DL-tert-Leucine with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product data.

How should DL-tert-Leucine be handled safely?

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Handling DL-tert-Leucine requires appropriate personal protective equipment, including eyeshields and gloves. A respirator filter of type N95 (US) or P1 (EN143) is recommended. Refer to the Safety Data Sheet for comprehensive handling information.

Is DL-tert-Leucine a controlled substance?

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The provided data does not indicate that DL-tert-Leucine (CAS: 33105-81-6) is a controlled substance.

How is DL-tert-Leucine packed, shipped, and exported?

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Tech Serve Solutions adheres to strict international shipping regulations for the packing and export of chemicals like DL-tert-Leucine, ensuring safe and compliant delivery worldwide.

How can I request a sample or quote for DL-tert-Leucine?

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To request a sample or a quotation for DL-tert-Leucine, please contact our sales team via the website or direct email, providing your specific requirements.

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