DL-Serine methyl ester hydrochloride
DL-Serine methyl ester hydrochloride (CAS: 5619-04-5) is a derivative of the amino acid serine, presenting as a hydrochloride salt. Its linear formula is HOCH₂CH(NH₂)CO₂CH₃·HCl, with a molecular weight of 155.58 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in peptide chemistry and the development of biochemical reagents. It is suitable for research and laboratory applications requiring a protected serine derivative.

Peptide Synthesis
DL-Serine methyl ester hydrochloride acts as a protected amino acid derivative, facilitating controlled coupling reactions in the synthesis of peptides and peptidomimetics.
Organic Synthesis Intermediate
This compound is a versatile intermediate in the synthesis of complex organic molecules, including pharmaceuticals and fine chemicals, where the serine moiety is required.
Biochemical Research
Utilised in biochemical studies and as a reagent for modifying proteins or exploring enzyme mechanisms that involve serine residues.
Chemical Biology
Serves as a tool in chemical biology for creating labelled molecules or investigating biological pathways involving amino acid derivatives.
| Molecular weight | 155.58 |
|---|---|
| Linear formula | HOCH2CH(NH2)CO2CH3·HCl |
| Storage temperature | −20°C |
| Melting point | 134-136 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is DL-Serine methyl ester hydrochloride used for?
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DL-Serine methyl ester hydrochloride is primarily used as a protected amino acid derivative in peptide synthesis, as an intermediate in organic synthesis, and in various biochemical and chemical biology research applications.
What is the CAS number and chemical formula for DL-Serine methyl ester hydrochloride?
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The CAS number is 5619-04-5, and the linear chemical formula is HOCH₂CH(NH₂)CO₂CH₃·HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies DL-Serine methyl ester hydrochloride as a research-grade chemical. The specific assay is not provided, and TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should DL-Serine methyl ester hydrochloride be handled safely?
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Handle with care. This compound is a Warning irritant to skin, eyes, and respiratory tract (H315, H319, H335). Use appropriate personal protective equipment, including eyeshields, gloves, and a P1 (EN143) or N95 (US) respirator filter, and ensure adequate ventilation. Avoid breathing dust. In case of contact with eyes, rinse cautiously with water for several minutes and remove contact lenses if present and easy to do. Continue rinsing.
How is DL-Serine methyl ester hydrochloride packaged and shipped?
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DL-Serine methyl ester hydrochloride is stored at -20°C. It is carefully packaged and exported by Tech Serve Solutions according to international shipping regulations for chemical compounds.
How can I request a sample or quote for DL-Serine methyl ester hydrochloride?
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To request a sample or a quote for DL-Serine methyl ester hydrochloride, please contact our sales team through the website or provide your details via the online inquiry form.
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