DL-Histidine monohydrochloride monohydrate
DL-Histidine monohydrochloride monohydrate (CAS: 123333-71-1; Formula: C6H9N3O2·HCl·H2O; MW: 209.63) is the mixed isomer of D- and L-histidine. This compound serves as a valuable reagent in various laboratory applications. It is particularly useful for evaluating the efficiency of amino acid chiral ligand exchange media and systems, and as a component in running buffers for capillary electrophoresis, contributing to separation science.
- IUPAC
- DL-α-Amino-β-(4-imidazolyl)propionic acid monohydrochloride
- Synonyms
- DL-α-Amino-β-(4-imidazolyl)propionic acid monohydrochloride

Chiral Chromatography Media Evaluation
DL-Histidine is employed to assess the performance and efficiency of amino acid-based chiral stationary phases (CSPs) used in liquid chromatography and other separation techniques.
Capillary Electrophoresis Buffers
This compound can be incorporated into running buffers for capillary electrophoresis (CE) to aid in the separation and analysis of analytes.
Biochemical Research
As a mixed isomer of histidine, it may find use in fundamental biochemical studies investigating amino acid behaviour and metabolism.
| Molecular weight | 209.63 |
|---|---|
| Empirical formula | C6H9N3O2 · HCl · H2O |
| Assay | ≥99% (TLC) |
| Application | DL-Histidine is the mixed isomer of D- and L-histidine. DL-Histidine may be used to evaluate the efficiency of amino acid chiral ligand exchange media and systems and in running buffers for capillary electrophoresis. |
| Melting point | 253 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is DL-Histidine monohydrochloride monohydrate used for?
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DL-Histidine monohydrochloride monohydrate is primarily used to evaluate the efficiency of amino acid chiral ligand exchange media and systems, and in running buffers for capillary electrophoresis.
What is the CAS number and formula for DL-Histidine monohydrochloride monohydrate?
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The CAS number is 123333-71-1, and the empirical formula is C6H9N3O2 · HCl · H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies DL-Histidine monohydrochloride monohydrate with an assay of ≥99% (TLC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should DL-Histidine monohydrochloride monohydrate be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and use a type N95 (US) or type P1 (EN143) respirator filter if necessary. It carries a WGK Germany rating of 3, indicating a high hazard level.
Is DL-Histidine monohydrochloride monohydrate a controlled substance?
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The provided data does not indicate that DL-Histidine monohydrochloride monohydrate is a controlled substance.
How is DL-Histidine monohydrochloride monohydrate shipped or exported?
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As a global supplier, Tech Serve Solutions professionally packs and exports chemicals worldwide, adhering to all relevant shipping and customs regulations.
How can I request a quote or sample of DL-Histidine monohydrochloride monohydrate?
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Please contact our sales team via the website or direct email to request a quotation or a sample of DL-Histidine monohydrochloride monohydrate.
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