Dipropylenetriamine NONOate
Dipropylenetriamine NONOate (CAS: 146724-95-0; Formula: C6H17N5O2; Molar Mass: 191.23 g/mol) is a nitric oxide (NO) donor. It is utilised in biochemical research as a tool to study cellular signalling pathways mediated by NO. Its controlled release of NO makes it valuable for investigating the physiological effects of NO in various biological systems, particularly in cell biology and neuroscience research.
- IUPAC
- 3,3′-(Hydroxynitrosohydrazino)bis-1-propanamine,DPTA NONOate
- Synonyms
- 3,3′-(Hydroxynitrosohydrazino)bis-1-propanamine,DPTA NONOate
Nitric Oxide Research
Dipropylenetriamine NONOate serves as a reliable source of nitric oxide for in vitro studies. Its sustained NO release profile allows researchers to investigate the long-term effects of NO in cellular processes, including vasodilation, neurotransmission, and immune responses.
Cell Signaling Studies
This compound is employed to probe the role of NO in cellular signalling cascades. By introducing controlled amounts of NO, researchers can elucidate signalling pathways involving guanylate cyclase activation and other NO-dependent mechanisms in various cell types.
Biochemical Reagent
As a biochemical reagent, Dipropylenetriamine NONOate is used in enzyme assays and studies involving nitric oxide synthase (NOS) activity or inhibition. Its predictable NO generation is crucial for quantifying enzyme kinetics and validating experimental models.
| Molecular weight | 191.23 |
|---|---|
| Empirical formula | C6H17N5O2 |
| Storage temperature | −70°C |
| Application | t1/2 NO release = 300 min (phosphate buffer at 22°C) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | dry ice |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dipropylenetriamine NONOate used for?
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Dipropylenetriamine NONOate is primarily used in biochemical research as a nitric oxide (NO) donor to study cellular signalling, cell biology, and neuroscience.
What are the CAS number and formula for Dipropylenetriamine NONOate?
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The CAS number is 146724-95-0 and the empirical formula (Hill notation) is C6H17N5O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Dipropylenetriamine NONOate for research purposes. The specific assay and purity are detailed on the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
How should Dipropylenetriamine NONOate be handled safely?
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Dipropylenetriamine NONOate is classified as harmful if swallowed and causes skin and serious eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area. Refer to the Safety Data Sheet for full handling instructions.
How is Dipropylenetriamine NONOate shipped and stored?
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Dipropylenetriamine NONOate is shipped on dry ice and requires storage at -70°C to maintain its stability and efficacy.
How can I request a sample or quote for Dipropylenetriamine NONOate?
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To request a sample or obtain a quote, please contact our sales department via the website or by phone, referencing the product name and CAS number.
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