Diphenylborinic anhydride
Diphenylborinic anhydride (CAS 4426-21-5) is a white to off-white crystalline solid with a molecular weight of 346.04 g/mol. This organoboron compound, also known as tetraphenyldiboroxane, is primarily utilised in chemical synthesis. It plays a role in the derivatisation of molecules for analytical purposes, particularly in the separation and determination of alpha-amino acids through the formation of boroxazolidones. Its structural similarity to known gap junction modulators also suggests applications in biochemical research.
- IUPAC
- Oxybis(diphenylborane),Tetraphenyldiboroxane
- Synonyms
- Oxybis(diphenylborane)Tetraphenyldiboroxane
Amino Acid Derivatisation
Diphenylborinic anhydride is employed in the chemical separation and quantification of alpha-amino acids. It achieves this by reacting with the amino acids to form stable boroxazolidone derivatives, facilitating their analysis.
Gap Junction Channel Studies
As an analogue of 2-aminoethoxydiphenyl borate (2-APB), a known vascular gap junction channel blocker, diphenylborinic anhydride is a valuable tool in research investigating the function and modulation of gap junction channels.
Reagent in Organic Synthesis
This compound serves as a useful reagent in various organic synthesis pathways, contributing to the construction of complex molecules and facilitating specific chemical transformations.
| Molecular weight | 346.04 |
|---|---|
| Linear formula | (C6H5)2BOB(C6H5)2 |
| Assay | 95% |
| Application | Diphenylborinic anhydride (DPBA) may be used for the separation and determination of α-amino acids by boroxazolidone formation. DPBA, an analogue of the vascular gap junction channel blocker, 2-aminoethoxydiphenyl borate (2-APB), may be use in gap junctions channel studies. |
| Melting point | 135-140 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 366 nm; λem 475 nm (after derivatization) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diphenylborinic anhydride used for?
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Diphenylborinic anhydride is used for the separation and determination of alpha-amino acids via boroxazolidone formation, and in studies of gap junction channels due to its structural similarity to known inhibitors.
What are the CAS number and formula for Diphenylborinic anhydride?
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The CAS number for Diphenylborinic anhydride is 4426-21-5. Its linear formula is (C₆H₅)₂BOB(C₆H₅)₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Diphenylborinic anhydride with a minimum assay of 95%. This product is intended for laboratory and research use; TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
How should Diphenylborinic anhydride be handled safely?
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Handling Diphenylborinic anhydride requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter is recommended. It is classified with WGK 2 in Germany, indicating it is hazardous to water.
How is Diphenylborinic anhydride typically shipped?
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Diphenylborinic anhydride is carefully packed and exported by Tech Serve Solutions, adhering to all relevant shipping regulations for chemical substances.
How can I request a quote or sample of Diphenylborinic anhydride?
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To request a quote or a sample of Diphenylborinic anhydride, please contact the Tech Serve Solutions sales team via our website or direct inquiry channels.
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