Diethyl fluoromalonate
Diethyl fluoromalonate (CAS: 685-88-1), with the linear formula FCH(COOC2H5)2 and a molecular weight of 178.16 g/mol, is a vital fluorinated organic building block. This ester compound is primarily utilized in chemical synthesis as a key intermediate. Its unique fluorinated structure allows for the introduction of fluorine atoms into various organic molecules, which is crucial in the development of novel pharmaceuticals and agrochemicals. Tech Serve Solutions supplies this compound with an assay of 97%.
Chemical Synthesis Intermediate
Diethyl fluoromalonate serves as a versatile building block in organic synthesis. It is employed to introduce fluorinated malonate moieties into more complex molecular structures, facilitating the creation of novel chemical entities.
Pharmaceutical Research
The compound's utility extends to pharmaceutical research and development, where fluorinated compounds often exhibit enhanced biological activity and metabolic stability. It can be a precursor for synthesizing active pharmaceutical ingredients (APIs).
Agrochemical Development
In the field of agrochemicals, the incorporation of fluorine can lead to compounds with improved efficacy and targeted action. Diethyl fluoromalonate can be used in the synthesis of new pesticides and herbicides.
Enzyme Activity Studies
The kinetic parameters of diethyl fluoromalonate have been instrumental in studying carboxylesterase activities within biological systems, offering insights into enzyme kinetics and inhibition.
| Molecular weight | 178.16 |
|---|---|
| Linear formula | FCH(COOC2H5)2 |
| Assay | 97% |
| Boiling point | 121-122 °C/30 mmHg(lit.) |
| Density | 1.129 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.407(lit.) |
| Application | The kinetic parameters of diethyl fluoromalonate in hemolysates were used to study carboxylesterase activities in complex systems1. |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 62 °C / 143.6 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diethyl fluoromalonate primarily used for?
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Diethyl fluoromalonate (CAS: 685-88-1) is primarily used as a building block in chemical synthesis, particularly for introducing fluorine into organic molecules for applications in pharmaceuticals and agrochemicals. It has also been used to study carboxylesterase activities.
What are the CAS number and formula for Diethyl fluoromalonate?
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The CAS number for Diethyl fluoromalonate is 685-88-1, and its linear formula is FCH(COOC2H5)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Diethyl fluoromalonate with a purity of 97% assay. This is a technical grade for research and synthesis purposes; TSS does not represent it as USP, BP, or EP grade.
How should Diethyl fluoromalonate be handled safely?
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Diethyl fluoromalonate is classified as a Danger substance, causing severe skin burns and eye damage (H314). Appropriate personal protective equipment, including gloves, goggles, and face shields, is essential. Use in a well-ventilated area with appropriate respiratory protection. Refer to the Safety Data Sheet for comprehensive handling instructions.
How is Diethyl fluoromalonate packed and shipped?
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Diethyl fluoromalonate is packed according to safety regulations for hazardous materials and is available for export globally by Tech Serve Solutions.
How can I request a quote or sample for Diethyl fluoromalonate?
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To request a quote or sample for Diethyl fluoromalonate, please contact the Tech Serve Solutions sales team through our website or by phone, providing your specific requirements and shipping details.
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