Diethyl chloromethylphosphonate
Diethyl chloromethylphosphonate (CAS 3167-63-3), molecular formula ClCH2PO(OC2H5)2, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.
- IUPAC
- Chloromethylphosphonic acid diethyl ester,NSC 67753

| Molecular weight | 186.57 |
|---|---|
| Linear formula | ClCH2PO(OC2H5)2 |
| Assay | 97% |
| Boiling point | 109-110 °C/10 mmHg(lit.) |
| Density | 1.2 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.437(lit.) |
| Application | Reactant involved in:• Subsequent alkylation after nucleophilic substitution1• One-pot alkylation-boration of α-haloalkylphosphonates2• Synthesis of cyclpentane and pyrrolidine derivatives via regioselective insertion reactions3• Phosphorylation leading to P-containing cyclopropanes4• Wadsworth-Emmons reactions5• Ring expansion of zircnacycles via carbenoid insertion6 |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 86 °C / 186.8 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diethyl chloromethylphosphonate?
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Diethyl chloromethylphosphonate (CAS 3167-63-3), molecular formula ClCH2PO(OC2H5)2, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to USP, BP and EP standards.
What grades of Diethyl chloromethylphosphonate does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Diethyl chloromethylphosphonate in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.
What is the CAS number and molecular formula of Diethyl chloromethylphosphonate?
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Diethyl chloromethylphosphonate has CAS number 3167-63-3 and molecular formula ClCH2PO(OC2H5)2. Full specifications appear in the table above and in the Certificate of Analysis.
What is the typical minimum order quantity and lead time for Diethyl chloromethylphosphonate?
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Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.
Do you provide a Certificate of Analysis (CoA) with each shipment?
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Yes. Every batch of Diethyl chloromethylphosphonate ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.
How should Diethyl chloromethylphosphonate be stored?
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Store Diethyl chloromethylphosphonate in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.
What is Diethyl chloromethylphosphonate used for?
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Diethyl chloromethylphosphonate is used in chemical synthesis applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.
How do I request a quote for Diethyl chloromethylphosphonate?
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Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.
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