Di-tert-amyl dicarbonate

CAS 68835-89-2[CH3CH2C(CH3)2OCO]2OChemical Synthesis

Di-tert-amyl dicarbonate (CAS 68835-89-2), with the chemical formula [CH3CH2C(CH3)2OCO]2O and a molecular weight of 246.30 g/mol, is a chemical reagent. It is primarily utilised in organic synthesis, particularly for the protection of amine groups. This compound serves as a valuable building block in the development of complex molecules within chemical biology and peptide chemistry.

IUPAC: (Amoc)2O,Di-tert-amyl pyrocarbonate,Di-tert-pentyl dicarbonate
Synonyms: Di-tert-pentyl dicarbonate

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Di-tert-amyl dicarbonate ([CH3CH2C(CH3)2OCO]2O) — chemical structure, CAS 68835-89-2; Chemistry, fine chemical supplied by Tech Serve Solutions

Amine ProtectionChemical BiologyChemical SynthesisOthersPeptide ChemistrySynthetic Reagents More...

01 /Applications

Amine Protection

Di-tert-amyl dicarbonate is employed as a protecting group reagent for amines in multi-step organic synthesis. The tert-amyl carbamate (Amoc) group it introduces can be selectively removed under specific conditions.

Peptide Synthesis

In peptide chemistry, this dicarbonate is used to protect the amino termini of amino acids or peptide fragments. This allows for controlled peptide bond formation during solid-phase or solution-phase synthesis.

Chemical Synthesis

The compound acts as a versatile reagent in general chemical synthesis, enabling the introduction of the tert-amyl carbamate protecting group. This is useful for modulating the reactivity of amine functionalities in various organic transformations.

Chemical Biology Research

Researchers in chemical biology may utilise Di-tert-amyl dicarbonate for synthesising modified biomolecules or probes where amine protection is required. It aids in the construction of specialised molecular structures for biological studies.

02 /Properties

Molecular weight	246.30
Linear formula	[CH3CH2C(CH3)2OCO]2O
Assay	97%
Boiling point	70 °C/0.05 mmHg(lit.)
Density	1.006 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.422(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US)
Flash point	104 °C / 219.2 °F
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

68835-89-2

MDL number

MFCD00038320

PubChem substance

24862112

Beilstein registry

2265846

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Di-tert-amyl dicarbonate primarily used for?

Di-tert-amyl dicarbonate is primarily used for the protection of amine groups in organic synthesis, particularly in peptide chemistry and broader chemical biology applications.

What are the CAS number and chemical formula for Di-tert-amyl dicarbonate?

The CAS number is 68835-89-2, and its chemical formula is [CH3CH2C(CH3)2OCO]2O.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Di-tert-amyl dicarbonate with an assay of 97%. We do not represent this product as USP, BP, or EP grade.

What are the key safety considerations when handling Di-tert-amyl dicarbonate?

Di-tert-amyl dicarbonate has a flash point of 104 °C (219.2 °F). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used. Always consult the Safety Data Sheet (SDS) before handling.

How is Di-tert-amyl dicarbonate packed, shipped, and exported?

Tech Serve Solutions packs, ships, and exports fine chemicals globally, adhering to all relevant transport regulations. Specific packaging details are available upon request.

How can I request a quote or sample for Di-tert-amyl dicarbonate?

You can request a quote or sample by contacting our sales team through the website or by calling our main office. Please reference the product name and CAS number (68835-89-2).