Dexamethasone
Dexamethasone (CAS: 50-02-2, Formula: C22H29FO5, MW: 392.46) is a potent synthetic glucocorticoid. Known for its strong anti-inflammatory and immunosuppressive properties, it is widely utilised in research settings for cell biology studies and chemical synthesis. Its precise activity and formulation suitability for cell culture make it a valuable reagent for biological and chemical investigations.
- IUPAC
- (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione,9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione,9α-Fluoro-16α-methylprednisolone,Prednisolone F
Cell Biology Research
Dexamethasone is frequently employed in cell culture experiments to modulate gene expression, study cellular responses to stress, and investigate signaling pathways. Its suitability for cell culture and defined potency make it a reliable tool for researchers.
Chemical Synthesis
As a complex organic molecule, Dexamethasone serves as a building block or reference compound in various chemical synthesis pathways. Its defined structure and purity are critical for reproducible synthetic outcomes.
Asymmetric Synthesis Applications
The chiral nature of Dexamethasone makes it relevant in asymmetric synthesis research, where stereochemistry is paramount. It can be used as a model compound or a starting material in complex chiral syntheses.
| Molecular weight | 392.46 |
|---|---|
| Empirical formula | C22H29FO5 |
| Assay | 98% |
| Solubility | H2O: soluble25 mg/mL, clear to slightly hazy |
| Optical activity | [α]25/D +77.5° in dioxane |
| Storage temperature | 2-8°C |
| Suitability | suitable for cell culture |
| Melting point | 262-264 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 36/37/38-42/43 |
| Safety statements (S) | 22-26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... NR3C1(2908) |
|---|---|
| Potency | 4-500 ng/mL |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dexamethasone used for?
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Dexamethasone is used in research for cell biology studies, chemical synthesis, and in asymmetric synthesis due to its potent biological activity and defined chemical structure.
What is the CAS number and formula for Dexamethasone?
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The CAS number for Dexamethasone is 50-02-2, and its molecular formula is C22H29FO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Dexamethasone with an assay of 98%. We do not represent this product as USP, BP, or EP grade. For specific lot analysis, please refer to the Certificate of Analysis.
How should Dexamethasone be handled safely?
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Dexamethasone presents hazards including skin and eye irritation, and respiratory irritation and sensitisation. Handle with appropriate personal protective equipment: a dust mask type N95 (US), eyeshields, face shields, and gloves. Ensure adequate ventilation.
Is Dexamethasone a controlled substance?
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This information is not available in the provided data. Please consult relevant national and international regulations regarding controlled substances.
How is Dexamethasone packed and exported?
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Dexamethasone is available for export and is carefully packed to maintain its integrity during transit. Storage at 2-8°C is recommended.
How can I request a sample or quote for Dexamethasone?
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Please contact Tech Serve Solutions directly through our website or sales channels to request a sample or a quotation for Dexamethasone.
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