[des-Gly10, D-His(Bzl)6]-LH-RH ethylamide

CAS 76712-82-8C66H86N18O12Cell Biology

[des-Gly10, D-His(Bzl)6]-LH-RH ethylamide (CAS 76712-82-8) is a synthetic peptide analogue with a molecular weight of 1323.50 g/mol. This compound is primarily utilised in biochemical research, particularly within cell biology and neuroscience. It serves as a valuable tool for studying cellular signalling pathways and neuropeptide functions. Supplied as a powder, this substance is intended for laboratory and research applications.

IUPAC: Histrelin
Synonyms: C66H86N18O12Histrelin

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[des-Gly10, D-His(Bzl)6]-LH-RH ethylamide (C66H86N18O12) — chemical structure, CAS 76712-82-8; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesCell BiologyLH-RHNeuropeptidesPeptides and ProteinsPeptides for Cell BiologyReleasing Factors More...

01 /Applications

Cell Biology Research

Utilised for in-vitro studies investigating cellular processes, signalling pathways, and biological responses to peptide stimuli. It serves as a research tool in understanding complex cellular mechanisms.

Neuroscience Studies

Applied in neuroscience research to explore the roles of neuropeptides and their receptors in the central nervous system. It aids in understanding neurological functions and potential therapeutic targets.

Biochemical Assays

Employed as a standard or reagent in biochemical assays requiring precise peptide concentrations and biological activity. Its defined composition makes it suitable for comparative studies.

02 /Properties

Molecular weight	1323.50
Empirical formula	C66H86N18O12
Assay	≥97% (HPLC)
Form	powder
Storage temperature	−20°C
Composition	Peptide content, ~70%

03 /Safety & handling

GHS hazard pictogram: Health hazard (GHS08) — Health hazard

Danger

Hazard statements

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use
P308IF exposed or concerned

Protective equipment	Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T
Risk statements (R)	60
Safety statements (S)	53-22-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

76712-82-8

MDL number

MFCD00133494

05 /Additional specifications

Gene Information	human ... GNRH1(2796), GNRHR(2798)mouse ... GNRH1(14714), GNRHR(14715)rat ... GNRH1(25194), GNRHR(81668)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is [des-Gly10, D-His(Bzl)6]-LH-RH ethylamide used for?

This compound is used in biochemical research, particularly within cell biology and neuroscience, to study cellular signalling pathways and neuropeptide functions.

What are the CAS number and formula for this product?

The CAS number is 76712-82-8, and the empirical formula is C66H86N18O12.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product with an assay of ≥97% (HPLC). TSS does not represent this product as USP, BP, or EP grade.

How should [des-Gly10, D-His(Bzl)6]-LH-RH ethylamide be handled?

This compound is classified as Danger (GHS08) and carries the hazard statement H360, indicating it may damage fertility or the unborn child. Appropriate personal protective equipment, including eyeshields, gloves, and specific respirator types (N100 US, P1/P3 EN143), is required. Handle only with adequate ventilation and follow precautionary statements P201 and P308 + P313.