D-(+)-Trehalose dihydrate
D-(+)-Trehalose dihydrate (CAS: 6138-23-4, C12H22O11 · 2H2O) is a disaccharide composed of two glucose units linked by an α,α-1,1-glycosidic bond. This stable, non-reducing sugar is known for its exceptional protective properties against dehydration and heat. It finds significant use in biochemical research, particularly for stabilizing proteins, enzymes, and cellular structures during storage, drying, or cryopreservation.
- IUPAC
- α,α-Trehalose,α-D-Glucopyranosyl-α-D-glucopyranoside
- Synonyms
- α,α-Trehalose,α-D-Glucopyranosyl-α-D-glucopyranoside

Biochemical Stabilisation
D-(+)-Trehalose dihydrate serves as an excellent excipient for stabilising sensitive biomolecules such as proteins, enzymes, and antibodies. Its glass-forming properties protect structures from denaturation during freeze-drying or storage.
Cryoprotection
The compound is employed as a cryoprotective agent to prevent cellular damage during freezing and thawing processes. It helps maintain cell viability by reducing ice crystal formation.
Research Reagent
Widely used in molecular biology and cell biology research, D-(+)-Trehalose dihydrate is valuable for various applications including cell culture media, enzyme assays, and maintaining the integrity of biological samples.
| Molecular weight | 378.33 |
|---|---|
| Empirical formula | C12H22O11 · 2H2O |
| Assay | ≥99.0% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 2 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D-(+)-Trehalose dihydrate used for?
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D-(+)-Trehalose dihydrate is primarily used as a stabilising agent for proteins, enzymes, and cells, particularly during dehydration, freeze-drying, and cryopreservation. It also serves as a cryoprotective agent and a general research reagent in biochemical and cell biology studies.
What are the CAS number and formula for D-(+)-Trehalose dihydrate?
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The CAS number for D-(+)-Trehalose dihydrate is 6138-23-4, and its empirical formula is C12H22O11 · 2H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies D-(+)-Trehalose dihydrate with an assay of ≥99.0%. This product is supplied for laboratory and research use and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling precautions for D-(+)-Trehalose dihydrate?
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D-(+)-Trehalose dihydrate is classified under WGK 2 in Germany. Recommended personal protective equipment includes eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter for airborne particulates. Avoid dust formation.
How is D-(+)-Trehalose dihydrate packed, shipped, and exported?
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As a global supplier, Tech Serve Solutions expertly packs, ships, and exports D-(+)-Trehalose dihydrate worldwide, adhering to all necessary regulations for safe and compliant transit.
How can I request a sample or quote for D-(+)-Trehalose dihydrate?
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To request a sample or obtain a quote for D-(+)-Trehalose dihydrate, please contact our sales team through the website or direct email, providing your specific requirements.
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