Coumachlor
Coumachlor (CAS: 81-82-3), with the empirical formula C19H15ClO4 and a molecular weight of 342.77 g/mol, is a significant chemical entity. It is recognised for its utility in chemical synthesis and as a building block, particularly within the realm of heterocyclic compounds. Its primary documented application involves its use as an internal standard in analytical chemistry, specifically for the enantioseparation of related compounds using advanced techniques like capillary electrochromatography coupled with mass spectrometry.
- IUPAC
- (±)-3-(α-Acetonyl-p-chlorobenzyl)-4-hydroxycoumarin,p-Chlorowarfarin
- Synonyms
- p-Chlorowarfarin
Analytical Standard
Coumachlor serves as an internal standard in the enantioseparation of warfarin enantiomers. This application is crucial for accurate quantification and chiral analysis in research settings.
Chemical Synthesis
As a heterocyclic building block, Coumachlor is valuable in organic synthesis. Its structure lends itself to the creation of more complex molecules, contributing to the development of novel chemical entities.
Research Reagent
Used in laboratory settings for research purposes, Coumachlor facilitates studies in analytical method development and organic chemistry.
| Molecular weight | 342.77 |
|---|---|
| Empirical formula | C19H15ClO4 |
| Assay | 98% |
| Solubility | acetone: solublealcohol: solublebenzene: slightly solublechloroform: solublediethyl ether: slightly solublewater: insoluble |
| Application | Coumachlor was used as internal standard for simultaneous enantioseparation of (+/-)-warfarin by chiral capillary electrochromatography with electrospray ionization mass spectrometry1. |
| Melting point | 168-170 °C(lit.) |
Hazard statements
- H373May cause damage to organs through prolonged exposure
- H412Harmful to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGI |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 48/22-52/53 |
| Safety statements (S) | 37-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Coumachlor used for?
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Coumachlor is used as an internal standard for the enantioseparation of warfarin and as a building block in chemical synthesis, particularly for heterocyclic compounds.
What is the CAS number and formula for Coumachlor?
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The CAS number for Coumachlor is 81-82-3, and its empirical formula is C19H15ClO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Coumachlor with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
What are the safety considerations for handling Coumachlor?
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Coumachlor carries hazard statements H373 (May cause damage to organs through prolonged or repeated exposure) and H412 (Harmful to aquatic life with long lasting effects). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, faceshields, and gloves, is recommended. Handling should be done in a well-ventilated area.
How is Coumachlor packed and shipped?
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Coumachlor is packed according to international shipping regulations for hazardous materials. As a global supplier and exporter, TSS ensures compliance for international orders.
How can I request a sample or quote for Coumachlor?
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To request a sample or a quote for Coumachlor, please contact the Tech Serve Solutions sales team through our website or by phone.
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