Corticosterone

CAS 50-22-6C21H30O4Biochemicals & Reagents

Corticosterone (CAS: 50-22-6), with the empirical formula C21H30O4 and a molecular weight of 346.46 g/mol, is a steroid hormone and a key glucocorticoid. It plays a significant role in the stress response and regulating physiological processes. Corticosterone is widely utilised as an analytical standard in various research and diagnostic applications, particularly in endocrinology and biochemical studies.

IUPAC: 11β,21-Dihydroxy-4-pregnene-3,20-dione,11β,21-Dihydroxyprogesterone,4-Pregnene-11β,21-diol-3,20-dione,Kendall’s Compound B,Reichstein’s Substance H
Synonyms: 11β,21-Dihydroxy-4-pregnene-3,20-dione11β,21-Dihydroxyprogesterone4-Pregnene-11β,21-diol-3,20-dioneKendall’s Compound BReichstein’s Substance H

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Corticosterone (C21H30O4) — chemical structure, CAS 50-22-6; Life Science, fine chemical supplied by Tech Serve Solutions

Analytical StandardsAnalytical/ChromatographyBioactive Small MoleculesBiochemicals and ReagentsCI-CYCO - CZCell BiologyChromatographyClinical StandardsHormones

01 /Applications

Analytical Standard

Used as a certified reference material for the accurate quantification and identification of corticosterone in biological samples and pharmaceutical preparations. It is crucial for method validation in analytical chemistry and quality control.

Biochemical Research

Investigates its role in stress pathways, immune responses, and metabolic regulation. Its availability as a high-purity standard facilitates in vitro and in vivo studies of steroid hormone action.

Endocrinology Studies

Essential for research into the hypothalamic-pituitary-adrenal (HPA) axis and the physiological effects of corticosteroids. Aids in understanding conditions related to adrenal function.

Chromatography Applications

Serves as a reference compound in chromatographic techniques such as HPLC and GC-MS for the separation and detection of steroid hormones. Ensures reliable identification and purity assessments.

02 /Properties

Molecular weight	346.46
Empirical formula	C21H30O4
Assay	≥92%
Grade	VETRANAL™, analytical standard
Melting point	179-183 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection

Protective equipment	dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	43
Safety statements (S)	36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

50-22-6

MDL number

MFCD00037715

Beilstein registry

2339601

05 /Additional specifications

Gene Information	human ... EBP(10682), SERPINA6(866)rat ... Ar(24208), Nr3c1(24413)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Corticosterone used for?

Corticosterone (CAS: 50-22-6) is primarily used as an analytical standard in biochemical and endocrinology research, particularly for studies involving the stress response and the HPA axis. It also finds application in chromatography for identification and quantification.

What are the CAS number and formula for Corticosterone?

The CAS number for Corticosterone is 50-22-6, and its empirical formula is C21H30O4.

What grade and purity does Tech Serve Solutions supply for Corticosterone?

Tech Serve Solutions supplies Corticosterone with an assay of ≥92% in a VETRANAL™, analytical standard grade. We do not represent this product as USP, BP, or EP grade.

What are the key safety considerations when handling Corticosterone?

Corticosterone is classified as a Warning with hazard statement H317 (May cause an allergic skin reaction). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, faceshields, and gloves, should be used. Handle in a well-ventilated area or fume hood.

How is Corticosterone packed and shipped by TSS?

Tech Serve Solutions professionally packs and exports Corticosterone globally. Specific packaging details are available upon request, adhering to all relevant shipping regulations for chemical substances.

How can I request a quote or sample for Corticosterone?

To request a quote or a sample of Corticosterone, please use the contact form on our website or reach out to our sales team directly, providing your specific requirements.