Copper(I) 3-methylsalicylate
Copper(I) 3-methylsalicylate (CAS 326477-70-7), with the empirical formula C8H7CuO3 and a molecular weight of 214.69 g/mol, is a copper complex utilized in organic synthesis. It serves as a catalyst for various transformations, including carbon-carbon bond formation, oxidative arylthiation, reductive cross-coupling, and oxidation reactions. This compound is a valuable reagent for chemical synthesis, offering specific catalytic properties for researchers and industrial applications.
- IUPAC
- CuMeSal,[2-(Hydroxy-κO)-3-methylbenzoato-κO]copper
- Synonyms
- [2-(Hydroxy-κO)-3-methylbenzoato-κO]copper

Carbon-Carbon Bond Formation
Copper(I) 3-methylsalicylate is employed as a catalyst to facilitate the formation of new carbon-carbon bonds. This is a fundamental transformation in organic chemistry, enabling the construction of complex molecular architectures.
Oxidative Arylthiation
This compound acts as a catalyst in oxidative arylthiation reactions. This process allows for the introduction of aryl groups and sulfur moieties into organic molecules, a key step in the synthesis of various pharmaceuticals and materials.
Reductive Cross-Coupling
Copper(I) 3-methylsalicylate catalyses reductive cross-coupling reactions. These reactions are essential for selectively joining different molecular fragments under reducing conditions.
Oxidation Reactions
The compound can be used as a catalyst to promote oxidation reactions. This includes the transformation of functional groups and the introduction of oxygen atoms into organic substrates.
Reductive Amination
Copper(I) 3-methylsalicylate finds application in catalysing reductive amination. This reaction is vital for synthesising amines, which are prevalent in many biologically active compounds.
| Molecular weight | 214.69 |
|---|---|
| Empirical formula | C8H7CuO3 |
| Application | Catalyst for:• Carbon-carbon bond formation1• Oxidative arylthiation2• Reductive cross-coupling3• Oxidation reactions4• Reductive amination5 |
| Melting point | 290-292 °C |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Copper(I) 3-methylsalicylate used for?
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Copper(I) 3-methylsalicylate (CAS 326477-70-7) is primarily used as a catalyst in various organic synthesis reactions, including carbon-carbon bond formation, oxidative arylthiation, reductive cross-coupling, oxidation reactions, and reductive amination.
What are the CAS number and empirical formula for Copper(I) 3-methylsalicylate?
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The CAS number for Copper(I) 3-methylsalicylate is 326477-70-7. Its empirical formula is C8H7CuO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Copper(I) 3-methylsalicylate as a research-grade chemical. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade, and specific purity details should be confirmed with our technical sales team.
What are the primary safety hazards associated with Copper(I) 3-methylsalicylate?
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Copper(I) 3-methylsalicylate is classified with GHS07 and a Warning signal word. It carries hazard statements H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Handle with appropriate personal protective equipment in a well-ventilated area.
How is Copper(I) 3-methylsalicylate packed and shipped?
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Copper(I) 3-methylsalicylate is carefully packed to ensure product integrity during transit. As a global supplier and exporter, Tech Serve Solutions adheres to all relevant shipping regulations for chemical products.
How can I request a quote or sample for Copper(I) 3-methylsalicylate?
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To request a quote or sample of Copper(I) 3-methylsalicylate, please contact our sales department directly through the website or by phone. Provide your contact details and the quantity required.
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