Cocaethylene
Cocaethylene (CAS: 529-38-4), with the molecular formula C18H23NO4 and a molecular weight of 317.38 g/mol, is a psychoactive alkaloid derived from coca. It is known for its stimulant and euphoric effects, produced by the body when ethanol is consumed concurrently with cocaine. This compound is primarily used in forensic and toxicological analysis, as well as a reference standard in research settings.
- IUPAC
- Ecgonine ethyl ester benzoate

Analytical Reference Standard
Cocaethylene serves as a critical reference standard in forensic toxicology and analytical chemistry laboratories for the identification and quantification of the substance in biological samples or seized materials.
Research Chemical
It is utilised in pharmacological and neuroscientific research to investigate the effects of combined cocaine and ethanol consumption on the central nervous system and related biological pathways.
Forensic Science Applications
Essential for forensic laboratories, this compound aids in the accurate determination of drug use and co-ingestion, contributing to legal and clinical investigations.
| Molecular weight | 317.38 |
|---|---|
| Empirical formula | C18H23NO4 |

Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Drug Control | USDEA Schedule II; Home Office Schedule 2; stup |
|---|---|
| Gene Information | mouse ... Slc6a2(20538)rat ... Slc6a3(24898), Slc6a4(25553) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cocaethylene used for?
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Cocaethylene is primarily used as an analytical reference standard in forensic toxicology and pharmacological research to study the effects of combined cocaine and ethanol consumption.
What are the CAS number and molecular formula for Cocaethylene?
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The CAS number for Cocaethylene is 529-38-4, and its molecular formula is C18H23NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Cocaethylene as a research-grade chemical. Purity details are available on the Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
How should Cocaethylene be handled and stored?
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Cocaethylene is classified as toxic if swallowed (H301) and requires careful handling. Use with appropriate personal protective equipment, including eyeshields, faceshields, gloves, and P2 respirator cartridges. Store in a secure, well-ventilated area, away from incompatible substances. Refer to the Safety Data Sheet (SDS) for comprehensive handling instructions.
Is Cocaethylene a controlled substance?
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Yes, Cocaethylene is a controlled substance, designated as US DEA Schedule II and Home Office Schedule 2 in the UK.
How is Cocaethylene packed and exported?
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Cocaethylene is packed in compliance with UN 2811 regulations for transport of infectious substances and biological samples, with a Packing Group III classification. TSS exports globally adhering to all relevant regulations.
How can I request a quote or sample of Cocaethylene?
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To request a quote or sample of Cocaethylene, please contact our sales team through the website or by calling us directly. Our team will provide prompt assistance.
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