cis-2-(Fmoc-amino)-cyclohexanecarboxylic acid
cis-2-(Fmoc-amino)-cyclohexanecarboxylic acid (CAS: 194471-85-7) is a unique alicyclic amino acid derivative with the molecular formula C22H23NO4 and a molecular weight of 365.42. Characterised by its cis stereochemistry and Fmoc protecting group, this compound serves as a valuable building block in complex organic synthesis, particularly within peptide chemistry and chemical biology research. Its structure allows for the introduction of constrained cyclic motifs into peptides.
- IUPAC
- Fmoc-1,2-cis-ACHC-OH
Peptide Synthesis
Utilised as a non-proteinogenic amino acid building block for incorporating cyclic and constrained structures into peptide chains. The Fmoc group facilitates standard solid-phase peptide synthesis protocols.
Chemical Biology Research
Serves as a tool for investigating protein structure-function relationships and developing novel peptidomimetics. Its rigid cyclic nature can influence biological activity and stability.
Organic Synthesis
A versatile intermediate for the synthesis of complex organic molecules. It provides a chiral cyclic scaffold for further chemical modifications and elaboration.
Drug Discovery
Incorporated into potential drug candidates to enhance metabolic stability or modulate binding affinity, owing to its unnatural amino acid structure.
| Molecular weight | 365.42 |
|---|---|
| Empirical formula | C22H23NO4 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
Hazard statements
- H413May cause long-lasting harmful effects to aquatic life
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is cis-2-(Fmoc-amino)-cyclohexanecarboxylic acid used for?
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cis-2-(Fmoc-amino)-cyclohexanecarboxylic acid is primarily used as a building block in peptide synthesis, chemical biology research, and complex organic synthesis, allowing for the introduction of cyclic motifs into molecules.
What are the CAS number and formula for this compound?
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The CAS number is 194471-85-7, and the empirical formula is C22H23NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies cis-2-(Fmoc-amino)-cyclohexanecarboxylic acid with an assay of ≥98.0% determined by HPLC. This product is not classified as USP, BP, EP, or any pharmacopoeia grade.
How should cis-2-(Fmoc-amino)-cyclohexanecarboxylic acid be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter. Store at 2-8°C. This compound may cause long lasting harmful effects to aquatic life (H413).
Is this product controlled or scheduled?
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The provided data does not indicate that cis-2-(Fmoc-amino)-cyclohexanecarboxylic acid is a controlled or scheduled substance.
How is this chemical exported or shipped?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, equipped to handle international shipments according to regulatory requirements.
How can I request a quote or sample?
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Please contact our sales team or use the online enquiry form on the Tech Serve Solutions website to request a quote or a sample of cis-2-(Fmoc-amino)-cyclohexanecarboxylic acid.
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