cis-2,3-Epoxybutane
cis-2,3-Epoxybutane (CAS: 1758-33-4), with the molecular formula C4H8O and a molecular weight of 72.11 g/mol, is a cyclic ether belonging to the epoxide class. This compound is valuable in organic synthesis and polymer science due to the reactivity of its strained epoxide ring. It serves as a monomer for the production of various polymers and as an intermediate in the synthesis of fine chemicals and pharmaceutical compounds.
- IUPAC
- cis-β-Butylene oxide,cis-2,3-Dimethyloxirane,cis-2-Butene oxide
- Synonyms
- C4H8Ocis-β-Butylene oxidecis-2,3-Dimethyloxiranecis-2-Butene oxide

Polymer Synthesis
cis-2,3-Epoxybutane can act as a monomer or co-monomer in the synthesis of polyethers and other specialized polymers. Its specific stereochemistry can influence the properties of the resulting polymer chains, making it useful for tailored material science applications.
Organic Synthesis Intermediate
The reactive epoxide group allows for ring-opening reactions with various nucleophiles. This makes cis-2,3-Epoxybutane a versatile building block for introducing specific functionalities in the synthesis of complex organic molecules, including pharmaceutical intermediates.
Research and Development
As a reactive epoxide, cis-2,3-Epoxybutane is employed in academic and industrial research settings to explore new reaction pathways, develop novel synthetic methodologies, and investigate the properties of new chemical entities.
| Molecular weight | 72.11 |
|---|---|
| Empirical formula | C4H8O |
| Assay | 97% |
| Boiling point | 60-61 °C(lit.) |
| Density | 0.826 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.383(lit.) |
| Melting point | −84-−83 °C(lit.) |


Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | -26 °C / -14.8 °F |
| Transport (UN / ADR) | UN 3271 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is cis-2,3-Epoxybutane primarily used for?
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cis-2,3-Epoxybutane is primarily used as a monomer in polymer synthesis and as an intermediate in organic synthesis for creating complex molecules and pharmaceutical precursors. It is also utilized in research and development settings.
What is the CAS number and chemical formula for cis-2,3-Epoxybutane?
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The CAS number for cis-2,3-Epoxybutane is 1758-33-4, and its molecular formula is C4H8O.
What grade and purity does Tech Serve Solutions supply for cis-2,3-Epoxybutane?
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Tech Serve Solutions supplies cis-2,3-Epoxybutane with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product documentation. It is typically supplied for research and industrial applications.
How should cis-2,3-Epoxybutane be handled safely?
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cis-2,3-Epoxybutane is a highly flammable liquid and vapour (H225) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Always handle in a well-ventilated area, away from ignition sources. Use appropriate personal protective equipment, including safety goggles, gloves, and respiratory protection, as indicated by the safety data sheet.
Is cis-2,3-Epoxybutane a controlled substance?
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The provided data does not indicate that cis-2,3-Epoxybutane is a controlled substance.
How is cis-2,3-Epoxybutane packed and shipped?
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cis-2,3-Epoxybutane is shipped as a hazardous material, UN 3271, Class 3, Packing Group II. It is carefully packed in compliance with international transportation regulations. Tech Serve Solutions exports fine chemicals globally.
How can I request a quote or sample of cis-2,3-Epoxybutane?
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To request a quote or a sample of cis-2,3-Epoxybutane, please visit the product page on our website and use the 'Request Quote' or 'Request Sample' function, or contact our sales team directly.
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