Cholic acid
Cholic acid (CAS: 81-25-4, C24H40O5) is a non-denaturing ionic detergent derived from ox or sheep bile, with a molecular weight of 408.57 g/mol. This bile acid is primarily utilised as a reagent for the extraction of membrane proteins. Its properties make it valuable in various biochemical and cell biology applications, including cell culture and antigen-vaccine preparation. Tech Serve Solutions offers Cholic Acid with an assay of ≥98%.
- IUPAC
- 3α,7α,12α-Trihydroxy-5β-cholanic acid,Cholanic acid
- Synonyms
- Cholanic acid3alpha,7alpha,12alpha-Trihydroxy-5beta-cholanic acid
Membrane Protein Extraction
Cholic acid serves as a non-denaturing ionic detergent. It is effectively used for the solubilisation and extraction of membrane proteins, preserving their native structure and function for subsequent analysis.
Biochemical Research
As a bile acid, it finds application in biochemical studies. It is employed in cell culture media and in the preparation of antigens and vaccines due to its biological origin and properties.
Detergent in Chromatography
Its detergent properties make it suitable for use in chromatography, particularly for separating or analysing complex biological mixtures where non-denaturing conditions are required.
| Molecular weight | 408.57 |
|---|---|
| Empirical formula | C24H40O5 |
| Assay | ≥98% |
| Application | Non-denaturing ionic detergent used for extraction of membrane proteins. |
| Biological source | from ox or sheep bile |
| Melting point | 200-201 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 2 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Description | anionic |
|---|---|
| Gene Information | human ... CYP1A2(1544) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cholic acid used for?
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Cholic acid is used as a non-denaturing ionic detergent for the extraction of membrane proteins and in various biochemical applications, including cell culture and antigen-vaccine preparation.
What are the CAS number and formula for Cholic acid?
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The CAS number for Cholic acid is 81-25-4, and its empirical formula is C24H40O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Cholic acid with an assay of ≥98%. We do not represent this product as USP, BP, or EP grade.
How should Cholic acid be handled?
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When handling Cholic acid, it is recommended to use safety precautions including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is a risk. Refer to the safety data sheet for comprehensive handling information.
How is Cholic acid packed and shipped?
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Cholic acid is packed and shipped according to industry best practices for chemical reagents, suitable for global export. Specific packaging details are available upon request.
How can I request a quote or sample for Cholic acid?
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To request a quote or a sample of Cholic acid, please contact our sales department through the website or provide your details via the online inquiry form.
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