Capsazepine
Capsazepine (CAS: 138977-28-3), a synthetic compound with the formula C19H21ClN2O2S and a molecular weight of 376.90 g/mol, is supplied by Tech Serve Solutions as an off-white solid. This molecule is recognised for its role in research, particularly within cell biology and neuroscience, serving as a valuable tool for investigating cellular signalling pathways. Its application extends to pharmacological studies, offering insights into complex biological mechanisms.
- IUPAC
- N-[2-(4-Chlorophenyl)ethyl]-1,3,4,5-tetrahydro-7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide
Neuroscience Research
Capsazepine is utilised in neuroscience to probe the function of specific ion channels, such as TRPV1 and TRPV4, aiding in the understanding of pain perception and sensory signalling.
Cellular Signaling Studies
This compound serves as a research tool to investigate intracellular calcium signalling and other related pathways in various cell types.
Pharmacological Investigations
As a vanilloid receptor antagonist, Capsazepine is employed in pharmacological research to explore the therapeutic potential of modulating these receptors.
| Molecular weight | 376.90 |
|---|---|
| Empirical formula | C19H21ClN2O2S |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | off-white |
| Solubility | methanol: soluble |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... TRPV1(7442), TRPV4(59341)rat ... Trpv1(83810) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Capsazepine used for?
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Capsazepine is primarily used in scientific research, particularly in neuroscience and cell biology, to study ion channel function and cellular signaling pathways. It acts as a research tool for investigating TRPV1 and TRPV4 receptors and related pharmacological mechanisms.
What is the CAS number and chemical formula for Capsazepine?
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The CAS number for Capsazepine is 138977-28-3, and its empirical formula is C19H21ClN2O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Capsazepine with a purity of ≥98% (HPLC). This product is intended for research and laboratory use only and is not supplied as USP, BP, EP, or pharmacopoeia grade.
What are the safety considerations when handling Capsazepine?
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When handling Capsazepine, it is essential to use personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound is classified under WGK Germany 3, indicating a high hazard to water.
How is Capsazepine shipped and exported by TSS?
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Tech Serve Solutions exports and ships Capsazepine under controlled conditions suitable for chemical reagents, adhering to all necessary regulations for global distribution.
How can I request a sample or quote for Capsazepine?
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To request a sample or obtain a quote for Capsazepine, please contact our sales team through the website or by direct inquiry, providing your specific requirements.
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