CAPS

CAS 1135-40-6C6H11NH(CH2)3SO3HBiochemicals & Reagents

CAPS (CAS: 1135-40-6), with the chemical formula C6H11NH(CH2)3SO3H and a molecular weight of 221.32 g/mol, is a zwitterionic buffer commonly used in biochemical and biological research. It offers good buffering capacity in the pH range of 9.7-11.1, making it suitable for applications requiring alkaline conditions. This high-purity buffer is essential for various molecular biology techniques and protein studies.

IUPAC: 3-(Cyclohexylamino)-1-propanesulfonic acid
Synonyms: 3-(Cyclohexylamino)-1-propanesulfonic acid

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CAPS (C6H11NH(CH2)3SO3H) — chemical structure, CAS 1135-40-6; Life Science, fine chemical supplied by Tech Serve Solutions

Biochemicals and ReagentsBiological BuffersBuffers A to ZBuffers and ReagentsBuffersReagents& StainsGood’s BuffersMolecular BiologyProtein Electrophoresis

01 /Applications

Biological Buffering

CAPS functions as an effective biological buffer, maintaining stable pH conditions in solutions within its useful range of 9.7 to 11.1. This is critical for enzymatic reactions and cellular assays that require alkaline environments.

Protein Electrophoresis and Proteomics

Its buffering properties make CAPS valuable in protein electrophoresis, including Western blotting. It helps to maintain pH during these processes, ensuring accurate separation and analysis of proteins.

Diagnostic Assay Manufacturing

Utilised in the diagnostics sector, CAPS serves as a key reagent in the manufacturing of assay kits. Its reliable performance ensures the consistency and accuracy of diagnostic tests.

Molecular Biology Research

CAPS is employed in various molecular biology applications where precise pH control is necessary. It supports research in areas such as nucleic acid manipulation and protein function studies.

02 /Properties

Molecular weight	221.32
Linear formula	C6H11NH(CH2)3SO3H
Assay	≥98.0%
Solubility	H2O: soluble0.5 M at 20 °C, clear, colorless
pH	3.5-6.0 (25 °C, 0.5 M in H2O)
Loss on drying	≤1% loss on drying, 110 °C
Impurities tested	insoluble matter, passes filter test
Melting point	>300 °C(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Faceshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3
Anion traces	chloride (Cl-): ≤50 mg/kgsulfate (SO42-): ≤150 mg/kg
Ignition residue	≤0.05%

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

1135-40-6

MDL number

MFCD00003837

PubChem substance

24892508

Beilstein registry

2835588

05 /Additional specifications

Pka 25 &#X00b0;C	10.4
Pka	10.4
Market Segment	Diagnostic Assay Manufacturing
Uv Absorption	λ: 260 nm Amax: 0.04λ: 280 nm Amax: 0.04
Ph Range	9.7 - 11.1
Useful Ph Range	9.7 - 11.1

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is CAPS used for?

CAPS is used as a biological buffer in molecular biology, protein electrophoresis, proteomics, and diagnostic assay manufacturing, particularly in the pH range of 9.7-11.1.

What is the CAS number and chemical formula for CAPS?

The CAS number for CAPS is 1135-40-6, and its chemical formula is C6H11NH(CH2)3SO3H.

What grade and purity does Tech Serve Solutions supply for CAPS?

Tech Serve Solutions supplies CAPS with an assay of ≥98.0%. We do not represent this product as USP, BP, or EP grade.

How should CAPS be handled safely?

Handle CAPS with appropriate personal protective equipment, including eyeshields, face shields, and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with WGK Germany of 3, indicating it is hazardous to water.