Caffeic acid
Caffeic acid (CAS 331-39-5) is a phenolic compound with the linear formula (HO)2C6H3CH=CHCO2H and a molecular weight of 180.16 g/mol. It is a naturally occurring antioxidant found in various plants, including onions and garlic. Caffeic acid is recognised for its biological activities and serves as a valuable building block in chemical synthesis and research applications.
- IUPAC
- 3,4-Dihydroxycinnamic acid
- Synonyms
- 3,4-Dihydroxycinnamic acid

Antioxidant Research
Caffeic acid is widely studied for its potent antioxidant properties. Its ability to scavenge free radicals makes it a valuable tool in research investigating oxidative stress and related biological processes.
Chemical Synthesis
As a functionalized cinnamic acid derivative, caffeic acid serves as a versatile building block in organic synthesis. It is employed in the creation of more complex molecules and pharmaceutical intermediates.
Epigenetic Studies
This compound is utilised in research focusing on epigenetics, particularly in investigating the role of small molecules in modulating gene expression and cellular function.
Natural Product Analysis
Caffeic acid is a marker compound in the analysis of various plant extracts, such as those from onions, garlic, and chamomile. Its presence and quantity can be indicative of the extract's composition and potential bioactivity.
| Molecular weight | 180.16 |
|---|---|
| Linear formula | (HO)2C6H3CH=CHCO2H |
| Assay | ≥95.0% (HPLC) |
| Grade | purum |
| Melting point | 211-213 °C (dec.)(lit.) |


Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
- H361Suspected of damaging fertility or the unborn child
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 63-36/37/38-40-68 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ELA2(1991)rat ... Alox5(25290) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Caffeic acid used for?
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Caffeic acid is used in antioxidant research, chemical synthesis as a building block, epigenetic studies, and as a marker in natural product analysis. It is also found in various plants such as onions, garlic, and horseradish.
What is the CAS number and formula for Caffeic acid?
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The CAS number for Caffeic acid is 331-39-5, and its linear formula is (HO)2C6H3CH=CHCO2H.
What grade and purity does Tech Serve Solutions supply for Caffeic acid?
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Tech Serve Solutions supplies Caffeic acid in purum grade with an assay of ≥95.0% by HPLC. We do not represent this product as USP, BP, or EP grade.
How should Caffeic acid be handled safely?
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Caffeic acid is classified with Warning signal word and carries hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), H335 (May cause respiratory irritation), H351 (Suspected of causing cancer), and H361 (Suspected of damaging fertility or the unborn child). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (type N100 or P3 filters), should be used. Ensure adequate ventilation.
Is Caffeic acid shipped internationally by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and reagents, including Caffeic acid.
How can I request a quote or sample for Caffeic acid?
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To request a quote or sample for Caffeic acid, please contact our sales team through the website or by phone.
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