Butyric anhydride
Butyric anhydride (CAS 106-31-0), with the linear formula (CH3CH2CH2CO)2O, is a clear, colourless liquid with a characteristic odour. This carboxylic acid anhydride is primarily utilised as a reagent in organic synthesis, particularly for acylation reactions. It serves as a valuable building block in the production of various chemical compounds, contributing to research and industrial chemical processes.
- IUPAC
- Butanoic anhydride
- Synonyms
- Butanoic anhydrideButyryl anhydride

Organic Synthesis Reagent
Butyric anhydride is frequently employed as an acylating agent in organic chemistry. It facilitates the introduction of the butyryl group into various molecules, playing a crucial role in the synthesis of complex organic structures and intermediates.
Chemical Intermediate
As a key building block, this compound is integral to the synthesis pathways of pharmaceuticals, agrochemicals, and speciality chemicals. Its reactivity allows for diverse chemical transformations essential in advanced chemical manufacturing.
Research and Development
In laboratory settings, butyric anhydride is used in R&D for exploring new synthetic routes and developing novel compounds. Its availability supports academic and industrial research efforts in various chemical disciplines.
| Molecular weight | 158.19 |
|---|---|
| Linear formula | (CH3CH2CH2CO)2O |
| Assay | 98% |
| Boiling point | 198-199 °C(lit.) |
| Density | 0.967 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.413(lit.) |
| Vapour pressure | 10 mmHg (79.5 °C) |
| Melting point | −75-−66 °C(lit.) |
| Vapour density | 5.45 (vs air) |
| Autoignition temp | 535 °F |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | 87 °C / 188.6 °F |
|---|---|
| Transport (UN / ADR) | UN 2739 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-34 |
| Safety statements (S) | 26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Expl Lim | 1.1 %, 104 °F7.6 %, 144 °F |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Butyric anhydride used for?
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Butyric anhydride is primarily used as a reagent in organic synthesis, particularly for acylation reactions, and as a chemical intermediate in the production of pharmaceuticals, agrochemicals, and other speciality chemicals.
What is the CAS number and formula for Butyric anhydride?
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The CAS number for Butyric anhydride is 106-31-0, and its linear formula is (CH3CH2CH2CO)2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Butyric anhydride with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should Butyric anhydride be handled safely?
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Butyric anhydride is corrosive and reacts violently with water. Handle with appropriate personal protective equipment, including gloves, eye protection, and protective clothing, in a well-ventilated area. Refer to the Safety Data Sheet for detailed handling instructions.
How is Butyric anhydride packed and shipped?
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Butyric anhydride is packed and shipped according to international regulations for hazardous materials. It is exported globally by Tech Serve Solutions.
How can I request a quote or sample of Butyric anhydride?
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Please contact Tech Serve Solutions directly via our website or sales department to request a quote or a sample of Butyric anhydride.
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