Bromopyruvic acid
Bromopyruvic acid (CAS: 1113-59-3), with the linear formula BrCH₂COCOOH and a molecular weight of 166.96 g/mol, is a valuable organic building block. It functions as a key intermediate in chemical synthesis and is notably recognised for its role in inhibiting aerobic glycolysis, also known as the Warburg Effect. This characteristic makes it significant in cancer metabolism and research, serving as a potent tool for scientific investigation.
- IUPAC
- 3-Bromo-2-oxopropionic acid
- Synonyms
- 3-Bromo-2-oxopropionic acid
Synthesis of Imidazo[1,2-a]pyridine-2-carboxylic Acids
Bromopyruvic acid serves as a crucial starting material in the synthesis of complex heterocyclic compounds, specifically imidazo[1,2-a]pyridine-2-carboxylic acids. This application highlights its utility in constructing fused ring systems important in medicinal chemistry.
Research in Cancer Metabolism
As a potent inhibitor of aerobic glycolysis (the Warburg Effect), bromopyruvic acid is extensively used in research to study cancer cell metabolism. It aids in understanding the biochemical pathways that drive tumor growth and proliferation.
Biochemical Pathway Investigation
The compound's ability to interfere with key glycolytic enzymes like hexokinase makes it a valuable reagent for dissecting cellular energy production pathways. Researchers employ it to elucidate the mechanisms of metabolic regulation in various biological systems.
| Molecular weight | 166.96 |
|---|---|
| Linear formula | BrCH2COCOOH |
| Assay | 98% |
| Solubility | water: soluble1 g/10 mL, clear, colorless |
| Storage temperature | 2-8°C |
| Application | Bromopyruvic acid was used in the synthesis of imidazo[1,2-a]pyridine-2-carboxylic acids1. |
| Melting point | 77-82 °C |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bromopyruvic acid primarily used for?
+
Bromopyruvic acid (CAS: 1113-59-3) is primarily used as a building block in chemical synthesis and as an inhibitor of aerobic glycolysis (the Warburg Effect) in cancer metabolism research. It is also used to study hexokinase inhibition and other biochemical pathways.
What are the CAS number and chemical formula for Bromopyruvic acid?
+
The CAS number for Bromopyruvic acid is 1113-59-3, and its linear formula is BrCH₂COCOOH.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Bromopyruvic acid with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should Bromopyruvic acid be handled and stored?
+
Bromopyruvic acid is a Danger hazard (H314) that causes severe skin burns and eye damage. Handle with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection. Store at 2-8°C.
How is Bromopyruvic acid packed and exported by TSS?
+
Bromopyruvic acid is shipped according to relevant dangerous goods regulations (UN 3261 8 / PGII). TSS is an experienced global supplier and exporter of fine chemicals.
How can I request a quote or sample for Bromopyruvic acid?
+
To request a quote or sample for Bromopyruvic acid, please contact our sales team through the website or by telephone, providing your specific requirements and shipping details.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis