Boc-β-(4-thiazolyl)-Ala-OH

CAS 119434-75-2C11H16N2O4SChemical Synthesis

Boc-β-(4-thiazolyl)-Ala-OH (CAS: 119434-75-2), with the molecular formula C11H16N2O4S and a molecular weight of 272.32 g/mol, is a protected unnatural amino acid derivative. It serves as a valuable building block in chemical synthesis, particularly within peptide chemistry and chemical biology. Its structure facilitates the incorporation of a thiazolyl-alanine moiety into peptides, enabling the study of protein structure and function.

IUPAC: (S)-2-(Boc-amino)-3-(4-thiazolyl)propionic acid,Boc-3-(4-thiazolyl)-L-alanine

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Boc-β-(4-thiazolyl)-Ala-OH (C11H16N2O4S) — chemical structure, CAS 119434-75-2; Chemistry, fine chemical supplied by Tech Serve Solutions

Alanine DerivativesChemical BiologyChemical SynthesisPeptide Chemistry

01 /Applications

Peptide Synthesis

Boc-β-(4-thiazolyl)-Ala-OH is utilised as a protected unnatural amino acid in solid-phase or solution-phase peptide synthesis. It allows for the introduction of a thiazole ring into peptide sequences, which can modulate biological activity or serve as a reporter group.

Chemical Biology Research

This compound is employed in chemical biology to construct peptides or peptidomimetics with unique structural or functional properties. The thiazolyl side chain can mimic histidine or participate in specific molecular interactions.

Medicinal Chemistry

As a building block, it is useful in medicinal chemistry for the development of novel therapeutic agents. Incorporating unnatural amino acids like this one can enhance peptide stability, bioavailability, or target binding affinity.

Organic Synthesis

Beyond peptides, Boc-β-(4-thiazolyl)-Ala-OH can be a precursor in the synthesis of complex organic molecules. The Boc protecting group offers selective reactivity control during multi-step synthetic routes.

02 /Properties

Molecular weight	272.32
Empirical formula	C11H16N2O4S
Assay	≥98.0% (HPLC)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

119434-75-2

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Boc-β-(4-thiazolyl)-Ala-OH used for?

Boc-β-(4-thiazolyl)-Ala-OH is used as a protected unnatural amino acid building block in peptide synthesis, chemical biology research, and medicinal chemistry for constructing peptides or organic molecules with a thiazolyl moiety.

What is the CAS number and molecular formula of Boc-β-(4-thiazolyl)-Ala-OH?

The CAS number is 119434-75-2, and the molecular formula is C11H16N2O4S.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Boc-β-(4-thiazolyl)-Ala-OH with an assay of ≥98.0% (HPLC). We do not represent this product as USP, BP, or EP grade.

What are the safety and handling precautions for this chemical?

Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. This compound has a WGK Germany classification of 3.

How is this chemical packed and shipped?

Tech Serve Solutions packs and exports fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, adhering to all relevant shipping and safety regulations.