Boc-3-(2-pyridyl)-Ala-OH
Boc-3-(2-pyridyl)-Ala-OH (CAS: 71239-85-5), with the molecular formula C13H18N2O4 and a molecular weight of 266.29, is a specialised amino acid derivative. It is a protected form of 3-(2-pyridyl)-alanine, featuring the tert-butyloxycarbonyl (Boc) protecting group. This compound is primarily utilised in peptide synthesis and medicinal chemistry research, offering a unique structural motif for drug discovery and development.
- IUPAC
- Boc-β-(2-pyridyl)-Ala-OH,Boc-3-(2-pyridyl)-L-alanine
Peptide Synthesis
This Boc-protected unnatural amino acid derivative is employed in solid-phase or solution-phase peptide synthesis to incorporate the 3-(2-pyridyl)-alanine residue into peptide chains. Its use allows for the construction of peptides with modified side chains, potentially influencing their biological activity or structural properties.
Medicinal Chemistry
The 3-(2-pyridyl)alanine moiety can serve as a valuable building block in the design of novel therapeutic agents. Researchers in medicinal chemistry utilise such unnatural amino acids to explore new pharmacophores and enhance the pharmacokinetic or pharmacodynamic profiles of drug candidates.
Chemical Biology Research
As an unnatural amino acid derivative, Boc-3-(2-pyridyl)-Ala-OH finds application in chemical biology for probing biological systems. It can be incorporated into peptides or peptidomimetics to study protein-ligand interactions, enzyme mechanisms, or other biological processes.
Organic Synthesis
The compound acts as a versatile intermediate in complex organic synthesis. The Boc protection and the pyridyl side chain offer distinct reactivity for further chemical modifications, enabling the creation of diverse molecular architectures.
| Molecular weight | 266.29 |
|---|---|
| Empirical formula | C13H18N2O4 |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]20/D −16.5±1.5°, c = 1% in methanol |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-3-(2-pyridyl)-Ala-OH used for?
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Boc-3-(2-pyridyl)-Ala-OH is primarily used as a building block in peptide synthesis, medicinal chemistry research, and organic synthesis due to its unnatural amino acid structure and Boc protecting group.
What are the CAS number and formula for Boc-3-(2-pyridyl)-Ala-OH?
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The CAS number is 71239-85-5, and the empirical formula is C13H18N2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-3-(2-pyridyl)-Ala-OH with an assay of ≥98.0% (TLC). We do not represent this product as USP, BP, or EP grade.
How should Boc-3-(2-pyridyl)-Ala-OH be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. It is classified as causing skin irritation, eye irritation, and respiratory irritation (H315, H319, H335).
Is this chemical exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Boc-3-(2-pyridyl)-Ala-OH.
How can I request a sample or quote?
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Please contact our sales department via the website or by phone to request a sample or obtain a quotation for Boc-3-(2-pyridyl)-Ala-OH.
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