Bis(trimethylsilyl)carbodiimide
Bis(trimethylsilyl)carbodiimide (CAS 1000-70-0), with the linear formula (CH3)3SiN=C=NSi(CH3)3 and a molecular weight of 186.40 g/mol, is a versatile synthetic reagent. It serves as a key reactant in the preparation of various organic molecules and advanced materials, including anticancer agents, O-silylurethanes, and silicon carbonitride compounds for protective coatings and ceramic applications.
- IUPAC
- 1,3-Bis(trimethylsilyl)carbodiimide,N,N′-Methanetetraylbis[1,1,1-trimethylsilylamine],N,N-Bis(trimethylsilyl)carbodiimide
- Synonyms
- 1,3-Bis(trimethylsilyl)carbodiimideN,N′-Methanetetraylbis[1,1,1-trimethylsilylamine]N,N-Bis(trimethylsilyl)carbodiimide

Synthesis of Anticancer Agents
Used as a reactant for preparing 4-substituted methoxylbenzoyl-aryl-thiazole analogues, which have demonstrated potential as potent and orally bioavailable anticancer agents.
Preparation of O-Silylurethanes
Acts as a crucial reactant in the synthesis of O-silylurethanes, contributing to the development of novel organic compounds.
Formation of Porous SiCN Materials
Employed in the synthesis of porous silicon carbonitride (SiCN) materials, relevant for advanced material science applications.
Production of Luminescent Diketo-pyrrolo-pyrrole Analogs
Serves as a reactant in the preparation of luminescent diketo-pyrrolo-pyrrole analogs, highlighting its utility in creating specialised organic molecules.
Development of Protective Coatings
Facilitates the creation of hard thin films of silicon carbonitride (SiCN) for potential use as protective coatings against wear and corrosion on metals.
Ceramic Material Synthesis
Functions as a reactant in the synthesis of ceramic materials, indicating its role in inorganic chemistry and materials science.
| Molecular weight | 186.40 |
|---|---|
| Linear formula | (CH3)3SiN=C=NSi(CH3)3 |
| Assay | ≥97.0% (GC) |
| Boiling point | 164 °C(lit.) |
| Density | 0.821 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.434(lit.)n20/D 1.434 |
| Application | Reactant for preparation of:• 4-substituted methoxylbenzoyl-aryl-thiazole analogues as potent and orally bioavailable anticancer agents1• O-silylurethanes2• Porous SiCN materials3• Luminescent diketo-pyrrolo-pyrrole analog4• Hard thin films of silicon carbonitride SiCN as potential protection coatings against wear and corrosion of metals5• Ceramic materials6 |
| Melting point | −23 °C(lit.) |


Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 21 °C / 69.8 °F |
| Transport (UN / ADR) | UN 1993BE 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bis(trimethylsilyl)carbodiimide used for?
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Bis(trimethylsilyl)carbodiimide is used as a reactant in the preparation of anticancer agents, O-silylurethanes, porous SiCN materials, luminescent diketo-pyrrolo-pyrrole analogs, protective SiCN coatings, and ceramic materials.
What are the CAS number and chemical formula for Bis(trimethylsilyl)carbodiimide?
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The CAS number is 1000-70-0 and the linear chemical formula is (CH3)3SiN=C=NSi(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Bis(trimethylsilyl)carbodiimide with a purity of ≥97.0% (GC). This product is intended for research and laboratory use; TSS does not represent it as USP, BP, EP, or pharmacopoeia grade.
What are the main safety hazards associated with Bis(trimethylsilyl)carbodiimide?
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Bis(trimethylsilyl)carbodiimide is a flammable liquid and vapour (H225). It is harmful if swallowed (H302) and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area.
How is Bis(trimethylsilyl)carbodiimide shipped and exported?
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Bis(trimethylsilyl)carbodiimide is shipped as a flammable liquid, UN 1993, Packing Group II. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, equipped to handle international shipping requirements.
How can I request a quote or sample for Bis(trimethylsilyl)carbodiimide?
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To request a quote or a sample, please contact our sales team through the website or by phone. We are available to assist with your specific requirements.
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