Bis(2-cyanoethyl)-N,N-diisopropylphosphoramidite
Bis(2-cyanoethyl)-N,N-diisopropylphosphoramidite (CAS 102690-88-0), with a molecular formula of C12H22N3O2P and a molecular weight of 271.30 g/mol, is a key reagent in chemical synthesis. Its applications primarily lie within chemical biology and nucleoside chemistry, serving as a valuable coupling reagent. This compound is supplied by Tech Serve Solutions with a purity of 95% and is carefully handled according to its significant hazard profile.
- IUPAC
- Bis(2-cyanoethoxy)(diisopropylamino)phosphine,Bis(2-cyanoethoxy)-N,N-diisopropylaminophosphine
- Synonyms
- C12H22N3O2PBis(2-cyanoethoxy)(diisopropylamino)phosphineBis(2-cyanoethoxy)-N,N-diisopropylaminophosphine
Nucleoside Chemistry
This phosphoramidite is instrumental in the synthesis of modified nucleosides and oligonucleotides. It facilitates the formation of phosphodiester bonds, crucial for building DNA and RNA analogues.
Chemical Synthesis Reagent
As a versatile coupling reagent, it finds application in various organic synthesis pathways. Its structure allows for controlled reactions in the preparation of complex molecules.
Chemical Biology Research
It is employed in the development of novel biochemical tools and probes. The compound aids in the study of biological processes at a molecular level.
| Molecular weight | 271.30 |
|---|---|
| Empirical formula | C12H22N3O2P |
| Assay | 95% |
| Density | 1.039 g/mL at 25 °C |
| Refractive index | n20/D 1.465 |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Flash point | 73 °C / 163.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,Xi |
| Risk statements (R) | 23-24-25-36-38 |
| Safety statements (S) | 26-36-37-39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bis(2-cyanoethyl)-N,N-diisopropylphosphoramidite used for?
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Bis(2-cyanoethyl)-N,N-diisopropylphosphoramidite (CAS 102690-88-0) is primarily used as a coupling reagent in nucleoside chemistry and for general chemical synthesis, particularly in chemical biology research.
What are the CAS number and formula for Bis(2-cyanoethyl)-N,N-diisopropylphosphoramidite?
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The CAS number is 102690-88-0 and the empirical formula (Hill notation) is C12H22N3O2P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Bis(2-cyanoethyl)-N,N-diisopropylphosphoramidite with a purity of 95%. This is a technical or research grade material and is not represented as USP, BP, or EP.
What are the primary safety hazards associated with this compound?
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This compound is classified as acutely toxic if swallowed, in contact with skin, or if inhaled (H301 + H311 + H331). It also causes skin irritation (H315) and serious eye irritation (H319). Handle with extreme caution in a well-ventilated area, using appropriate personal protective equipment.
How is Bis(2-cyanoethyl)-N,N-diisopropylphosphoramidite packed and shipped?
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As a hazardous material (UN 2810, Class 6.1, PGIII), this chemical is packaged and shipped according to stringent international regulations for dangerous goods. We are experienced global exporters.
How can I request a quote or sample?
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To request a quote or a sample of Bis(2-cyanoethyl)-N,N-diisopropylphosphoramidite, please contact our sales team via the website or direct inquiry. We will respond promptly.
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