Berbamine dihydrochloride
Berbamine dihydrochloride (CAS: 6078-17-7), with the molecular formula C37H40N2O6 ·2HCl and a molecular weight of 681.65 g/mol, is a vital chemical compound. It serves as a key reactant in various chemical synthesis pathways, notably in the preparation of biologically active berbamine derivatives with potential anti-leukemia properties. This compound is recognised for its role in asymmetric synthesis and chiral chemistry.
- IUPAC
- berbenine
Preparation of Anti-Leukemia Derivatives
Berbamine dihydrochloride is utilized as a precursor in the synthesis of novel berbamine derivatives, which have demonstrated anti-leukemia activity. This application underscores its importance in medicinal chemistry research and drug discovery.
Asymmetric Synthesis and Chiral Chemistry
The compound's structure and properties make it a valuable building block in asymmetric synthesis. It can be employed in reactions requiring chiral control, contributing to the development of enantiomerically pure compounds.
Phytochemical Research
As a derivative of compounds found in Berberis species, berbamine dihydrochloride is a subject of study in phytochemical research, particularly concerning its biological activities and potential therapeutic applications.
| Molecular weight | 681.65 |
|---|---|
| Empirical formula | C37H40N2O6 ·2HCl |
| Optical activity | [α]20/D +116°, c = 1% in ethanol |
| Application | Reactant for:• Preparation of and anti-leukemia active berbamine derivatives1 |
| Melting point | 250-253 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Berbamine dihydrochloride used for?
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Berbamine dihydrochloride is primarily used as a reactant for the preparation of and anti-leukemia active berbamine derivatives. It also finds application in asymmetric synthesis and phytochemical research.
What are the CAS number and formula for Berbamine dihydrochloride?
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The CAS number for Berbamine dihydrochloride is 6078-17-7, and its empirical formula is C37H40N2O6 ·2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Berbamine dihydrochloride. The exact grade and purity are available on the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should Berbamine dihydrochloride be handled safely?
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Berbamine dihydrochloride is a Warning substance, harmful if swallowed (H302), and causes skin (H315), eye (H319), and respiratory tract irritation (H335). Use with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure good ventilation.
How is Berbamine dihydrochloride packed and shipped?
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Berbamine dihydrochloride is securely packed according to industry standards to ensure safe transit and compliance with international shipping regulations. Tech Serve Solutions is a global exporter.
How can I request a sample or quote for Berbamine dihydrochloride?
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To request a sample or a quote for Berbamine dihydrochloride, please contact our sales department via the website or directly by email, providing your specific requirements.
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