Benzophenone-4-isothiocyanate
Benzophenone-4-isothiocyanate (CAS: 26328-59-6, C14H9NOS) is a photoreactive reagent with a molecular weight of 239.29 g/mol. It is valuable for researchers in cell biology and chemical synthesis, particularly for creating photoreactive peptides and oligonucleotides. This compound serves as a key building block in advanced biochemical research and the development of specialised biological probes.

Photoreactive Labeling
Utilised in the synthesis of photoreactive peptides and oligonucleotides. Its benzophenone moiety allows for light-activated covalent crosslinking to biological molecules.
Chemical Biology Probes
Serves as a versatile reagent for developing chemical probes to study biological interactions. Enables the study of protein-nucleic acid interactions through photoaffinity labelling.
Bioconjugation
Facilitates the conjugation of molecules to biomacromolecules with spatial control upon UV irradiation. Useful in creating targeted delivery systems or diagnostic tools.
| Molecular weight | 239.29 |
|---|---|
| Empirical formula | C14H9NOS |
| Storage temperature | −20°C |
| Application | A benzophenone-based photoreactive reagent shown to be useful for synthesizing photoreactive peptides and oligonucleotides. |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Mol Wt | mol wt 239.29 |
|---|---|
| Shipped In | dry ice |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Benzophenone-4-isothiocyanate used for?
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Benzophenone-4-isothiocyanate is used for synthesizing photoreactive peptides and oligonucleotides, serving as a reagent in chemical biology and bioconjugation for photoaffinity labelling.
What are the CAS number and formula for Benzophenone-4-isothiocyanate?
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The CAS number is 26328-59-6, and the empirical formula is C14H9NOS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical as a research-grade product. We do not represent it as USP, BP, EP, or pharmacopoeia grade. Purity details are available upon request or via the certificate of analysis.
How should Benzophenone-4-isothiocyanate be handled safely?
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Benzophenone-4-isothiocyanate is classified as Danger (GHS05) with hazard statement H314, indicating it causes severe skin burns and eye damage. Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, must be used. Handle in a well-ventilated area.
How is Benzophenone-4-isothiocyanate shipped and stored?
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This product is shipped in dry ice and should be stored at -20°C to maintain its stability and integrity.
How can I request a quote or sample?
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Please contact our sales team directly via the website or by phone to request a quotation or a sample of Benzophenone-4-isothiocyanate.
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