Benzenesulfonyl isocyanate
Benzenesulfonyl isocyanate (CAS: 2845-62-7, Formula: C6H5SO2NCO, MW: 183.18) is a reactive organic compound employed as a versatile building block in chemical synthesis. It is particularly useful for creating sterically hindered derivatives of phenols and alcohols, and for modifying semi-crystalline polymers. Its isocyanate group readily reacts with nucleophiles, making it valuable for introducing the benzenesulfonyl moiety into various molecular structures for research and development.
Synthesis of Hindered Phenols and Alcohols
Benzenesulfonyl isocyanate reacts with phenols and alcohols to yield sterically hindered derivatives. This application is crucial for the preparation of specialised organic compounds with unique properties for further synthetic elaboration.
Polymer Modification
This reagent has been utilised to chemically modify semi-crystalline poly(ether ether ketone) (PEEK) films. The reaction introduces carbonyl functionalities, altering the surface properties of the polymer for specific applications.
Organic Building Block
As a key organic building block, benzenesulfonyl isocyanate facilitates the introduction of the benzenesulfonyl group into diverse molecular frameworks. Its reactivity makes it suitable for complex synthetic strategies in academic and industrial research.
| Molecular weight | 183.18 |
|---|---|
| Linear formula | C6H5SO2NCO |
| Assay | 95% |
| Boiling point | 130 °C/9 mmHg(lit.) |
| Density | 1.369 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.536(lit.) |
| Storage temperature | 2-8°C |
| Application | Benzenesulfonyl isocyanate was used in synthesis of sterically hindered derivatives of phenols and alcohols1. It was also used in the reaction of semi crystalline poly(ether ether ketone) films with carbonyl selective reagents to produce modified film samples2. |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 2922 6.1(8) / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/22-36/38-42 |
| Safety statements (S) | 23-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Benzenesulfonyl isocyanate used for?
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Benzenesulfonyl isocyanate is primarily used as a building block in chemical synthesis, notably for preparing sterically hindered derivatives of phenols and alcohols, and for modifying polymers like PEEK.
What are the CAS number and formula for Benzenesulfonyl isocyanate?
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The CAS number for Benzenesulfonyl isocyanate is 2845-62-7, and its molecular formula is C6H5SO2NCO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Benzenesulfonyl isocyanate with a minimum assay of 95%. We do not represent this product as USP, BP, or EP grade; it is supplied for technical and research purposes.
How should Benzenesulfonyl isocyanate be handled safely?
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Benzenesulfonyl isocyanate is hazardous. It is harmful if swallowed or inhaled, causes skin irritation, may cause an allergic skin reaction, causes serious eye irritation, and may cause allergy or asthma symptoms or breathing difficulties if inhaled. Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (e.g., type ABEK respirator filter), must be used in a well-ventilated area.
Is Benzenesulfonyl isocyanate a controlled substance?
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Based on the provided data, Benzenesulfonyl isocyanate is not indicated as a controlled substance.
How is Benzenesulfonyl isocyanate packed and shipped?
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Benzenesulfonyl isocyanate is supplied according to standard chemical packaging procedures for hazardous materials and is available for global export. Please contact us for specific shipping details.
How can I request a sample or quote for Benzenesulfonyl isocyanate?
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To request a sample or a quotation for Benzenesulfonyl isocyanate, please use the contact form on our website or reach out to our sales department directly.
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