Benzamidine

CAS 618-39-3C6H5C(=NH)NH2Chemical Synthesis

Benzamidine (CAS: 618-39-3), with the molecular formula C6H5C(=NH)NH2 and a molecular weight of 120.15 g/mol, is a key organic building block. It functions as an amidine derivative and is recognised for its utility in biochemical research and chemical synthesis. Benzamidine is particularly noted for its role as a serine protease inhibitor and has been employed in studies involving proteoglycan isolation and the purification of specific protein factors.

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Benzamidine (C6H5C(=NH)NH2) — chemical structure, CAS 618-39-3; Chemistry, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesBuilding BlocksCell BiologyChemical SynthesisImines/AmidinesNitrogen Compounds

01 /Applications

Biochemical Research Applications

Benzamidine has been utilised in research for the preparation of heparan sulfate-rich proteoglycans from specific cell types. Its properties are valuable in biochemical assays and studies involving protein purification.

Protease Inhibition in Protein Purification

This compound serves as an effective protease inhibitor, preventing enzymatic degradation during the isolation and purification of sensitive protein factors, such as bovine factor XII (Hageman factor).

Organic Synthesis Building Block

As an organic building block, Benzamidine is employed in chemical synthesis for the creation of more complex molecular structures. Its imine and amidine functionalities offer versatile reaction pathways.

02 /Properties

Molecular weight	120.15
Linear formula	C6H5C(=NH)NH2
Application	Benzamidine was used in the preparation of heparan sulfate-rich proteoglycan from mouse mammary epithelial cells1. It has been used to prevent enzymatic degradation during the purification procedure of bovine factor XII (Hageman factor)2.

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed
H319Causes serious eye irritation

Precautionary statements

P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22-36
Safety statements (S)	26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

618-39-3

MDL number

MFCD00042826

Beilstein registry

606020

05 /Additional specifications

Gene Information	human ... F10(2159), F2(2147), PLAT(5327), PLAU(5328), PLG(5340), PRSS1(5644)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Benzamidine used for?

Benzamidine is used in biochemical research, for instance, in the preparation of heparan sulfate-rich proteoglycans, and as a protease inhibitor to prevent enzymatic degradation during the purification of proteins like bovine factor XII. It also serves as an organic building block in chemical synthesis.

What are the CAS number and chemical formula for Benzamidine?

The CAS number for Benzamidine is 618-39-3, and its chemical formula is C6H5C(=NH)NH2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Benzamidine as a research-grade chemical. We do not represent this product as USP, BP, or EP grade.

How should Benzamidine be handled safely?

Benzamidine is harmful if swallowed and causes serious eye irritation (H302, H319). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, face shields, and gloves. Ensure good ventilation.

How is Benzamidine packed, shipped, and exported?

Benzamidine is carefully packed to maintain its integrity during transit. Tech Serve Solutions is experienced in global export procedures for fine chemicals and laboratory reagents.

How can I request a sample or quote for Benzamidine?

To request a sample or a quote for Benzamidine, please contact our sales department through the website or by phone, providing your specific requirements.