Benz[cd]indol-2(1H)-one
Benz[cd]indol-2(1H)-one (CAS: 130-00-7, C11H7NO) is a heterocyclic organic compound with a molecular weight of 169.18 g/mol. This indole derivative serves as a valuable building block in chemical synthesis. Its applications include participation in photo-Fries rearrangements and as a reactant in the preparation of potential antitumor agents and inhibitors of thymidylate synthase.
- IUPAC
- NSC 25094
![Benz[cd]indol-2(1H)-one (C11H7NO) — chemical structure, CAS 130-00-7; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F130-00-7.png&w=3840&q=75)
Photo-Fries Rearrangement
Benz[cd]indol-2(1H)-one acts as a reactant in photo-Fries rearrangement reactions, a photochemical process for the synthesis of phenolic ketones.
Antitumor Agent Synthesis
This compound is utilised as a reactant in the development pathways for potential antitumor agents, contributing to medicinal chemistry research.
Thymidylate Synthase Inhibitors
It serves as a key reactant in the synthetic routes aimed at producing inhibitors of thymidylate synthase, an important target in cancer therapy.
| Molecular weight | 169.18 |
|---|---|
| Empirical formula | C11H7NO |
| Solubility | methanol: soluble25 mg/mL, clear to slightly hazy, yellow to brown |
| Application | • Reactant in photo-Fries rearrangement1• Reactant in preparation of potential antitumor agents2• Reactant in synthesis of inhibitors of thymidylate synthase3 |
| Melting point | 173-178 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Benz[cd]indol-2(1H)-one used for?
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Benz[cd]indol-2(1H)-one is used as a reactant in photo-Fries rearrangement reactions, and in the preparation of potential antitumor agents and inhibitors of thymidylate synthase.
What is the CAS number and formula for Benz[cd]indol-2(1H)-one?
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The CAS number is 130-00-7, and the molecular formula is C11H7NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound for research and development purposes. The exact purity and grade are available upon request; it is not supplied as USP, BP, or EP grade.
How should Benz[cd]indol-2(1H)-one be handled?
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Handle Benz[cd]indol-2(1H)-one with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. It is classified as harmful if swallowed (H302).
Can Tech Serve Solutions export Benz[cd]indol-2(1H)-one?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Benz[cd]indol-2(1H)-one.
How can I request a sample or quote for Benz[cd]indol-2(1H)-one?
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To request a sample or quote, please contact our sales team through the website or by phone, providing the product name and CAS number.
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