Azoxymethane
Azoxymethane (CAS: 25843-45-2), with the molecular formula CH3N=N(→O)CH3 and a molecular weight of 74.08 g/mol, is a chemical compound utilised in laboratory settings. It functions as a gene mutation agent. Primarily, it is employed in conjunction with dextran sulfate sodium (DSS) to establish cancer models in research animals, aiding the study of cancer progression mechanisms and chemoprevention strategies.
- IUPAC
- AOM
Cancer Research Models
Azoxymethane is used in combination with dextran sulfate sodium (DSS) to induce colorectal cancer models in laboratory animals. These models are crucial for investigating the molecular pathways of carcinogenesis and evaluating potential chemopreventive agents.
Carcinogenesis Studies
As a known gene mutation agent, Azoxymethane serves as a valuable tool for researchers studying the fundamental mechanisms of cancer development and the genetic alterations associated with it.
Cell Biology Research
The compound's ability to induce mutations makes it useful in cellular studies focused on DNA damage, repair mechanisms, and the long-term effects of genotoxic agents on cell populations.
| Molecular weight | 74.08 |
|---|---|
| Linear formula | CH3N=N(→O)CH3 |
| Assay | ≥90% (GC) |
| Boiling point | 97-99 °C(lit.) |
| Density | 0.991 g/mL at 25 °C(lit.) |
| Concentration | 13.4 M |
| Storage temperature | −20°C |
| Contains / stabiliser | ≤15% ethanol and acetic acid (Packaged based on azoxymethane.) |
| Application | Azoxymethane (AOM), a gene mutation agent, may be used with dextran sulfate sodium (DSS) to create cancer models in laboratory animals which can be used to study mechanisms of cancer progression and chemoprevention. |
Hazard statements
- H300Fatal if swallowed
- H350May cause cancer
Precautionary statements
- P201Obtain special instructions before use
- P264Wash thoroughly after handling
- P301IF SWALLOWED
- P305IF IN EYES
- P308IF exposed or concerned
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 45-46-25 |
| Safety statements (S) | 53-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Azoxymethane used for?
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Azoxymethane (AOM) is primarily used in cancer research, often in conjunction with dextran sulfate sodium (DSS), to create cancer models in laboratory animals for studying disease progression and chemoprevention. It functions as a gene mutation agent.
What is the CAS number and chemical formula for Azoxymethane?
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The CAS number for Azoxymethane is 25843-45-2, and its chemical formula is CH3N=N(→O)CH3.
What grade and purity does Tech Serve Solutions supply for Azoxymethane?
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Tech Serve Solutions supplies Azoxymethane with an assay of ≥90% (GC). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmaceutical grade.
How should Azoxymethane be handled and stored?
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Azoxymethane is classified with a 'Danger' signal word and carries significant hazards (H300: Fatal if swallowed, H350: May cause cancer). It requires extremely careful handling in a well-ventilated area, use of appropriate personal protective equipment (gloves, eye protection, respiratory protection), and storage at -20°C. Refer to the Safety Data Sheet for comprehensive handling instructions.
Is Azoxymethane a controlled substance?
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Based on the provided safety data, Azoxymethane is classified under UN 2810 with hazard class 6.1 (Toxic substances) and Packing Group III. Its specific status as a controlled substance may vary by jurisdiction, and users should verify local regulations.
How is Azoxymethane packed and exported by TSS?
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Azoxymethane is typically packaged based on the azoxymethane content, which may contain up to 15% ethanol and acetic acid. Tech Serve Solutions exports fine chemicals globally, adhering to international shipping regulations for hazardous materials.
How can I request a quote or sample for Azoxymethane?
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To request a quote or obtain a sample of Azoxymethane, please contact the Tech Serve Solutions sales team through our website or via the provided contact information, specifying the required quantity and your research application.
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