Azetidine
Azetidine (CAS: 503-29-7; Formula: C3H7N; MW: 57.09) is a saturated heterocyclic amine. This colourless liquid is a valuable building block in organic synthesis, particularly for creating more complex nitrogen-containing molecules. Its applications include palladium-catalyzed cross-coupling reactions with aryl bromides and Ullmann-type coupling reactions with iodonitrofluorenes. Azetidine is supplied by Tech Serve Solutions with a minimum assay of 98%.
- IUPAC
- Trimethylene imine
Palladium-Catalyzed Cross-Coupling Reactions
Azetidine can participate in palladium-catalyzed cross-coupling reactions with aryl bromides, serving as a key reagent in the formation of new carbon-nitrogen bonds.
Ullmann-Type Coupling Reactions
This compound is employed in Ullmann-type coupling reactions, for instance, with iodonitrofluorenes, enabling the synthesis of specific heterocyclic structures.
Heterocyclic Compound Synthesis
As a fundamental N-containing heterocyclic building block, Azetidine is instrumental in the synthesis of diverse and complex organic molecules.
| Molecular weight | 57.09 |
|---|---|
| Empirical formula | C3H7N |
| Assay | 98% |
| Boiling point | 61-62 °C(lit.) |
| Density | 0.847 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.432(lit.) |
| Storage temperature | 2-8°C |
| Application | Azetidine was employed in:• a high yielding palladium-catalyzed cross-coupling raection with aryl bromides1• Ullmann type coupling reaction with iodonitroflourenes2 |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | -21 °C / -5.8 °F |
| Transport (UN / ADR) | UN 2733 3/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-34 |
| Safety statements (S) | 16-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Azetidine primarily used for?
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Azetidine is primarily used as a building block in organic synthesis, particularly for palladium-catalyzed cross-coupling reactions with aryl bromides and Ullmann-type coupling reactions.
What are the CAS number and molecular formula for Azetidine?
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The CAS number for Azetidine is 503-29-7, and its molecular formula is C3H7N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Azetidine with a minimum assay of 98%. This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, or EP grade.
How should Azetidine be handled safely?
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Azetidine is a highly flammable liquid and vapour (H225) and causes severe skin burns and eye damage (H314). Handle with extreme care in a well-ventilated area, wearing appropriate personal protective equipment including gloves, eye protection, and respiratory protection. Store at 2-8°C.
How is Azetidine shipped and exported?
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Azetidine is shipped and exported according to international regulations for hazardous materials, classified under UN 2733, Class 3, Packing Group II. Tech Serve Solutions is an experienced global supplier.
How can I request a quote or sample for Azetidine?
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To request a quote or sample for Azetidine, please contact our sales team through the website or call us directly. We will be pleased to assist you.
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