Arachidonyl trifluoromethyl ketone
Arachidonyl trifluoromethyl ketone (CAS: 149301-79-1) is a trifluoromethyl ketone with the molecular formula C21H31F3O and a molecular weight of 356.47 g/mol. This yellow oily substance is primarily recognised for its role as an inhibitor of Phospholipase A2 (PLA2). It serves as a valuable tool in biochemical research, particularly in studies involving cell signalling, neuroscience, and inflammation pathways, owing to its specific enzyme inhibitory properties.
- IUPAC
- 1,1,1-Trifluoromethyl-6,9,12,15-heieicosatetraen-2-one,AACOCF3,Arach-CF3
- Synonyms
- 1,1,1-Trifluoromethyl-6,9,12,15-eicosatetraen-2-oneAACOCF3Arach-CF3
Enzyme Inhibition Studies
Arachidonyl trifluoromethyl ketone is a potent inhibitor of Phospholipase A2 (PLA2). It is widely used in research to investigate the biological roles of PLA2 enzymes in various cellular processes, including inflammation and cell signalling.
Neuroscience Research
As a modulator of pathways involving PLA2, this compound finds application in neuroscience research. It aids in understanding the complex signalling mechanisms within the nervous system where arachidonic acid metabolism plays a crucial role.
Biochemical Tool
This chemical serves as a valuable biochemical reagent for laboratory research. Its specific inhibitory action allows for the targeted study of enzyme kinetics and biological pathways in vitro.
| Molecular weight | 356.47 |
|---|---|
| Empirical formula | C21H31F3O |
| Assay | ≥97% (NMR) |
| Form | oil |
| Colour | yellow |
| Solubility | DMSO: >5 mg/mL |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... PLA2G1B(5319) |
|---|---|
| Storage Condition | desiccatedprotect from light |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Arachidonyl trifluoromethyl ketone used for?
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Arachidonyl trifluoromethyl ketone is primarily used as an inhibitor of Phospholipase A2 (PLA2) in biochemical and cell biology research, particularly in studies of cell signalling and neuroscience.
What are the CAS number and formula for Arachidonyl trifluoromethyl ketone?
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The CAS number is 149301-79-1 and the empirical formula is C21H31F3O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Arachidonyl trifluoromethyl ketone with an assay of ≥97% (NMR). This product is intended for research use and is not represented as USP, BP, EP, or other pharmacopoeial grades.
What are the safety and handling precautions for Arachidonyl trifluoromethyl ketone?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A half-mask respirator (EU or US) with a multi-purpose combination cartridge (US) is recommended. The compound has a WGK rating of 3 in Germany, indicating a high hazard.
How is Arachidonyl trifluoromethyl ketone stored and shipped?
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It should be stored desiccated and protected from light at -20°C. TSS ensures proper packaging and export compliance for this chemical.
How can I request a quote or sample?
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Please contact our sales team via the website to request a quote or a sample of Arachidonyl trifluoromethyl ketone.
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