Allylmagnesium chloride solution
Allylmagnesium chloride solution (CAS 2622-05-1), with the linear formula CH₂=CHCH₂MgCl and a molar mass of 100.83 g/mol, is a highly reactive organometallic reagent. Supplied as a 2.0 M solution in Tetrahydrofuran (THF), it is primarily utilised as a nucleophile in organic synthesis. Its applications include facilitating the study of nucleophilic ring-opening reactions in aziridines and subsequent transformations into hydantoin derivatives. This Grignard reagent demands careful handling due to its flammability and reactivity.
Nucleophilic Ring-Opening Reactions
Allylmagnesium chloride solution is employed in studies investigating the nucleophilic ring-opening of 2-methyleneaziridines. This reaction leads to the formation of imines, which can be further transformed into valuable hydantoin structures.
Grignard Reagent in Organic Synthesis
As a Grignard reagent, it serves as a potent nucleophile for carbon-carbon bond formation. Its allyl moiety can be readily introduced into various organic molecules, enabling the synthesis of complex structures.
Synthesis of Heterocyclic Compounds
The compound is instrumental in the synthesis of heterocyclic compounds, specifically contributing to the formation of substituted hydantoins through a multi-step process involving ring-opening and subsequent cyclisation.
| Molecular weight | 100.83 |
|---|---|
| Linear formula | CH2=CHCH2MgCl |
| Density | 0.995 g/mL at 25 °C |
| Concentration | 2.0 M in THF |
| Application | Used in a study of the nucleophilic ring-opening of 2-methyleneaziridines to imines and subsequent conversion to 5,5′-disubstituted hydantoins.1 |
Hazard statements
- H225Highly flammable liquid and vapour
- H250Catches fire spontaneously if exposed to air
- H260In contact with water releases flammable gases
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P222Do not allow contact with air
- P223Do not allow contact with water
- P231Handle under inert gas
- P370In case of fire
- P422
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -17 °C / 1.4 °F |
| Transport (UN / ADR) | UN 3399 4.3/PG 1 |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14/15-19-34-37 |
| Safety statements (S) | 16-26-36/37/39-43-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Allylmagnesium chloride solution used for?
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Allylmagnesium chloride solution (CAS 2622-05-1) is used in organic synthesis, particularly for studying the nucleophilic ring-opening of 2-methyleneaziridines to imines and their subsequent conversion to 5,5′-disubstituted hydantoins. It functions as a Grignard reagent for carbon-carbon bond formation.
What is the CAS number and formula for Allylmagnesium chloride solution?
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The CAS number is 2622-05-1 and the linear formula is CH₂=CHCH₂MgCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Allylmagnesium chloride solution at a concentration of 2.0 M in THF. We do not claim USP, BP, EP, or pharmacopoeia grades unless explicitly stated in the product specifications. This product is intended for research and chemical synthesis purposes.
How should Allylmagnesium chloride solution be handled safely?
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Allylmagnesium chloride solution is highly flammable and reacts violently with water. It causes severe skin burns and eye damage and may cause respiratory irritation. Handle under an inert atmosphere, away from heat and ignition sources. Wear appropriate personal protective equipment, including gloves, eye protection, and respiratory protection. Store in a cool, well-ventilated area, tightly sealed.
Is Allylmagnesium chloride solution shipped or exported?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Allylmagnesium chloride solution, adhering to all international shipping and export regulations.
How can I request a sample or quote for Allylmagnesium chloride solution?
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To request a sample or a quote for Allylmagnesium chloride solution, please visit the Tech Serve Solutions website or contact our sales team directly. Provide your contact details and the quantity required.
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