Adenosine 5′-diphosphoribose sodium salt
Adenosine 5′-diphosphoribose sodium salt (CAS: 68414-18-6; Formula: C15H23N5O14P2) is a biochemical reagent with a molecular weight of 559.32 g/mol. It serves as a fundamental building block and substrate for the synthesis of poly(ADP-ribose) by poly(ADP-ribose) polymerase enzymes. This process is integral to cellular DNA repair mechanisms and apoptosis signaling pathways. Supplied by Tech Serve Solutions, it is essential for research in molecular biology and cellular signalling.
- IUPAC
- ADP-Ribose
Poly(ADP-ribose) Synthesis
Acts as a direct substrate for poly(ADP-ribose) polymerases (PARPs). This enzymatic activity is crucial for the formation of poly(ADP-ribose) chains, a key post-translational modification.
DNA Repair Research
The poly(ADP-ribose) synthesis pathway, initiated by this substrate, plays a vital role in cellular responses to DNA damage, making it a critical component in DNA repair studies.
Apoptosis Signaling Studies
Involved in the signaling cascades that lead to programmed cell death (apoptosis). Its role in PARP activation links it to the regulation of apoptotic processes.
Biochemical Research
Used as a standard reagent in biochemical and enzymatic assays related to nucleotide metabolism and signalling pathways.
| Molecular weight | 559.32 |
|---|---|
| Empirical formula | C15H23N5O14P2 |
| Assay | ≥93% |
| Storage temperature | −20°C |
| Application | ADP-Ribose is used as the basic building block used as a substrate in the formation of poly(ADP-ribose) by members of the poly(ADP-ribose) polymerase (PARP) family. Poly(ADP-ribose) formation and degradation are an important components of DNA repair and apoptosis signaling. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Adenosine 5′-diphosphoribose sodium salt used for?
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Adenosine 5′-diphosphoribose sodium salt is used as a substrate in the formation of poly(ADP-ribose) by PARP enzymes, which is important for DNA repair and apoptosis signalling.
What is the CAS number and formula for Adenosine 5′-diphosphoribose sodium salt?
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The CAS number is 68414-18-6 and the empirical formula is C15H23N5O14P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Adenosine 5′-diphosphoribose sodium salt with an assay of ≥93%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmaceutical grade.
How should Adenosine 5′-diphosphoribose sodium salt be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask type N95, eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation, as it may cause skin, eye, and respiratory irritation (H315-H319-H335).
Is Adenosine 5′-diphosphoribose sodium salt available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Adenosine 5′-diphosphoribose sodium salt.
How can I request a sample or quote for Adenosine 5′-diphosphoribose sodium salt?
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Please contact our sales team via the website or by phone to request a sample or a detailed quotation for Adenosine 5′-diphosphoribose sodium salt.
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