Acetyl-β-methylcholine chloride
Acetyl-β-methylcholine chloride (CAS 62-51-1), with the molecular formula C7H16ClNO2 and a molecular weight of 195.69 g/mol, is a choline ester and an analogue of acetylcholine. This compound functions as a receptor agonist. It is primarily utilised in scientific research to investigate physiological processes, notably airway hyperresponsiveness associated with asthma, by stimulating cholinergic receptors.
- IUPAC
- (2-Acetoxypropyl)trimethylammonium chloride,Methacholine chloride
- Synonyms
- (2-Acetoxypropyl)trimethylammonium chlorideMethacholine chloride
Pharmacological Research
Acetyl-β-methylcholine chloride serves as a valuable tool in pharmacological research, acting as a cholinergic agonist. It is employed to study the mechanisms of muscarinic receptors and their role in various physiological responses.
Asthma and Airway Studies
This compound is instrumental in research models of asthma and other respiratory conditions. It is used to induce and study airway hyperresponsiveness, providing insights into disease pathogenesis and potential therapeutic targets.
Neuroscience Research
As a choline ester, Acetyl-β-methylcholine chloride aids in the investigation of neurotransmission and cholinergic signaling pathways within the nervous system. Its actions on muscarinic receptors are relevant to understanding neurological functions.
| Molecular weight | 195.69 |
|---|---|
| Linear formula | CH3COOCH(CH3)CH2N(Cl)(CH3)3 |
| Assay | ≥98% (TLC) |
| Form | powder |
| Solubility | H2O: soluble50 mg/mL (solutions undergo rapid, pH-dependent decomposition at pH > 6.) |
| Storage temperature | −20°C |
| Application | Acetyl-β-methylcholine (methacholine), an analog of acetylcholine, is use as a receptor agonist to study processes such as airway hyperresponsiveness associated with asthma. |
| Melting point | 171-173 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Acetyl-β-methylcholine chloride used for?
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Acetyl-β-methylcholine chloride is used in research as a receptor agonist, particularly to study airway hyperresponsiveness associated with asthma and to investigate cholinergic signaling in neuroscience.
What are the CAS number and formula for Acetyl-β-methylcholine chloride?
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The CAS number is 62-51-1, and the linear formula is CH3COOCH(CH3)CH2N(Cl)(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Acetyl-β-methylcholine chloride with a purity of ≥98% (TLC). We do not represent this product as USP, BP, or EP grade.
How should Acetyl-β-methylcholine chloride be handled safely?
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Handling Acetyl-β-methylcholine chloride requires appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (type N95 US). It is classified as harmful if swallowed and causes skin and eye irritation, and respiratory irritation (H302, H315, H319, H335). Work in a well-ventilated area and avoid dust formation.
How is Acetyl-β-methylcholine chloride typically shipped or exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific shipping and export details for Acetyl-β-methylcholine chloride can be provided upon request.
How can I request a sample or quote for Acetyl-β-methylcholine chloride?
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To request a sample or a quote for Acetyl-β-methylcholine chloride, please contact our sales team through the website or by phone.
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