Acetophenone tosylhydrazone
Acetophenone tosylhydrazone (CAS 4545-21-5) is an organic compound with the linear formula C<sub>6</sub>H<sub>5</sub>C(CH<sub>3</sub>)=NNHSO<sub>2</sub>C<sub>6</sub>H<sub>4</sub>CH<sub>3</sub> and a molecular weight of 288.36 g/mol. It is a derivative of acetophenone and p-toluenesulfonic acid. Primarily utilised as a versatile building block in organic synthesis, it serves as a key intermediate in the preparation of various complex molecules and heterocyclic compounds.
- IUPAC
- p-Toluenesulfonic acid (α-methylbenzylidene)hydrazide
- Synonyms
- p-Toluenesulfonic acid (α-methylbenzylidene)hydrazide

Organic Synthesis Intermediate
Acetophenone tosylhydrazone acts as a crucial building block in organic chemistry. It facilitates the synthesis of diverse organic molecules, particularly in the formation of new carbon-nitrogen bonds and heterocyclic structures.
Research and Development
This compound is frequently employed in academic and industrial research settings for exploring novel synthetic pathways and developing new chemical entities. Its reactivity makes it valuable for complex molecule construction.
Precursor for Heterocyclic Compounds
The hydrazone functionality allows for cyclization reactions, making it a useful precursor for synthesizing various nitrogen-containing heterocyclic compounds, which are important in medicinal chemistry and material science.
| Molecular weight | 288.36 |
|---|---|
| Linear formula | C6H5C(CH3)=NNHSO2C6H4CH3 |
| Assay | 97% |
| Melting point | 144-149 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Acetophenone tosylhydrazone used for?
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Acetophenone tosylhydrazone is primarily used as a building block and intermediate in organic synthesis, particularly for the preparation of complex organic molecules and heterocyclic compounds. It is also widely used in research and development for exploring new synthetic methodologies.
What is the CAS number and chemical formula for Acetophenone tosylhydrazone?
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The CAS number for Acetophenone tosylhydrazone is 4545-21-5. Its linear formula is C<sub>6</sub>H<sub>5</sub>C(CH<sub>3</sub>)=NNHSO<sub>2</sub>C<sub>6</sub>H<sub>4</sub>CH<sub>3</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Acetophenone tosylhydrazone with a minimum assay of 97%. This product is suitable for general laboratory and synthetic use. TSS does not represent this product as USP, BP, EP or any other pharmacopoeia grade.
What are the safety precautions for handling Acetophenone tosylhydrazone?
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When handling Acetophenone tosylhydrazone, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. Refer to the Safety Data Sheet (SDS) for detailed hazard information and handling procedures.
How is Acetophenone tosylhydrazone packed and shipped?
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Acetophenone tosylhydrazone is carefully packed to ensure safe transit and compliance with international shipping regulations. Tech Serve Solutions has extensive experience in exporting chemicals globally.
How can I request a quote or sample of Acetophenone tosylhydrazone?
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To request a quote or sample of Acetophenone tosylhydrazone, please contact our sales team through the website or by calling us directly. Our team will be pleased to assist with your enquiry.
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