Ac-YVAD-cmk
Ac-YVAD-cmk (CAS: 178603-78-6) is a chemical compound with the molecular formula C24H33ClN4O8 and a molecular weight of 540.99 g/mol. This white to off-white powder is primarily utilized as a specific inhibitor in biochemical research. It plays a crucial role in studying apoptosis and cell cycle regulation by targeting caspase enzymes, particularly caspase-1. Available from Tech Serve Solutions, it is essential for researchers in cell biology and neuroscience.
- IUPAC
- Ac-Tyr-Val-Ala-Asp-Chloromethylketone,N-Acetyl-L-tyrosyl-L-valyl-N-[(1S)-1-(carboxymethyl)-3-chloro-2-oxopropyl]-L-alaninamide,N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketone
- Synonyms
- Ac-Tyr-Val-Ala-Asp-ChloromethylketoneN-Acetyl-L-tyrosyl-L-valyl-N-[(1S)-1-(carboxymethyl)-3-chloro-2-oxopropyl]-L-alaninamideN-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketone
Caspase Inhibition
Ac-YVAD-cmk serves as a potent and specific inhibitor of caspase-1 (ICE). This makes it an invaluable tool for researchers investigating the role of caspase-1 in apoptosis, inflammation, and other cellular processes.
Apoptosis Research
By inhibiting key executioner caspases like caspase-1, Ac-YVAD-cmk aids in the elucidation of apoptotic pathways. This enables scientists to better understand programmed cell death mechanisms in various biological contexts.
Cell Signaling Studies
This inhibitor is employed to dissect complex cell signaling cascades, particularly those involving inflammatory responses and programmed cell death. Its specificity allows for targeted investigation of caspase-dependent signaling.
| Molecular weight | 540.99 |
|---|---|
| Empirical formula | C24H33ClN4O8 |
| Assay | ≥95% (HPLC) |
| Form | powder |
| Colour | white to off-white |
| Storage temperature | −20°C |
| Shipped In | wet ice |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ac-YVAD-cmk used for?
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Ac-YVAD-cmk is a specific inhibitor of caspase-1, used in research for studying apoptosis, cell cycle regulation, and cell signaling pathways, particularly those involving inflammatory responses.
What are the CAS number and formula for Ac-YVAD-cmk?
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The CAS number for Ac-YVAD-cmk is 178603-78-6, and its empirical formula is C24H33ClN4O8.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ac-YVAD-cmk with a purity of ≥95% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Ac-YVAD-cmk be handled?
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Ac-YVAD-cmk is classified under WGK Germany 2, indicating it is hazardous to water. Handle with appropriate personal protective equipment and avoid release into the environment.
How is Ac-YVAD-cmk shipped and exported?
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Ac-YVAD-cmk is shipped in wet ice to maintain its stability and integrity during transit. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals.
How can I request a sample or quote for Ac-YVAD-cmk?
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To request a sample or obtain a quote for Ac-YVAD-cmk, please contact our sales team through the website or by phone.
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