9-Anthracenecarbonyl cyanide
9-Anthracenecarbonyl cyanide (CAS 85985-44-0, C16H9NO, MW: 231.25) is a specialized fluorescent reagent primarily employed for the derivatization of glucocorticoids. Its reactive nature allows for the formation of fluorescent esters with primary hydroxyl groups, crucial for detection and separation via RP-HPLC with fluorescence detection. This compound is supplied by Tech Serve Solutions for research and development purposes.
- IUPAC
- α-Oxo-anthracene-9-acetonitrile,9-Anthroyl nitrile
- Synonyms
- α-Oxo-anthracene-9-acetonitrile,9-Anthroyl nitrile
Glucocorticoid Derivatization
9-Anthroyl nitrile serves as a derivatizing agent for glucocorticoids, specifically reacting with the primary hydroxyl group at the 21-carbon position to form fluorescent esters. This enhances their detectability in analytical procedures.
Fluorescence Detection in HPLC
The fluorescent derivatives formed by 9-anthracenecarbonyl cyanide are amenable to sensitive detection using fluorescence detection systems coupled with Reverse-Phase High-Performance Liquid Chromatography (RP-HPLC).
Analytical Chemistry Reagent
This compound is valuable in analytical laboratories for developing methods to quantify and separate complex steroid molecules, particularly glucocorticoids, leveraging its fluorescent labeling capabilities.
| Molecular weight | 231.25 |
|---|---|
| Empirical formula | C16H9NO |
| Assay | ≥98.5% (GC) |
| Solubility | DMF: solubleacetonitrile: solublechloroform: soluble |
| Storage temperature | −20°C |
| Application | 9-Anthroyl nitrile is a fluorescent reagent useful in the derivatization of glucocorticoids to aid their detection and separation using RP-HPLC with fluorescence detection. It forms fluorescent esters by reacting with primary the hydroxyl group at the position 21 of the carbon chain on the glucocorticoid 1,2. |
| Suitability | suitable for fluorescence |
| Melting point | 142-143 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-29 |
| Safety statements (S) | 36-43 |
| Supplemental hazards | Contact with water liberates toxic gas. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Product Line | BioReagent |
|---|---|
| Fluorescence | λex 361 nm; λem 451 nm (after derivatization with ethanol)λex 361 nm; λem 460 nm in methanol |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 9-Anthracenecarbonyl cyanide used for?
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9-Anthracenecarbonyl cyanide is used as a fluorescent derivatization reagent for glucocorticoids, facilitating their detection and separation using RP-HPLC with fluorescence detection.
What is the CAS number and molecular formula for 9-Anthracenecarbonyl cyanide?
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The CAS number is 85985-44-0 and the molecular formula is C16H9NO.
What grade and purity does Tech Serve Solutions supply for 9-Anthracenecarbonyl cyanide?
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Tech Serve Solutions supplies 9-Anthracenecarbonyl cyanide with an assay of ≥98.5% (GC). This product is not represented as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated.
How should 9-Anthracenecarbonyl cyanide be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Be aware that contact with water liberates toxic gas. Store at -20°C.
Is 9-Anthracenecarbonyl cyanide suitable for fluorescence detection?
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Yes, 9-Anthracenecarbonyl cyanide is suitable for fluorescence detection after derivatization, with characteristic excitation and emission wavelengths provided in the product details.
How is 9-Anthracenecarbonyl cyanide packed, shipped, and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, adhering to all necessary regulations for packing, shipping, and exporting 9-Anthracenecarbonyl cyanide.
How can I request a quote or sample for 9-Anthracenecarbonyl cyanide?
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Please contact our sales team through the website to request a quote or sample for 9-Anthracenecarbonyl cyanide.
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